Specialization of the left supramarginal gyrus for hand-independent praxis representation is not related to hand dominance.
Specialization of the left supramarginal gyrus for hand-independent praxis representation is not related to hand dominance.
复制标题
DOI：
10.1016/j.neuropsychologia.2016.03.023
复制
发表时间：
2016-12
期刊：
影响因子：
2.6
通讯作者：
Frey SH
中科院分区：
文献类型：
--
作者：
Króliczak G;Piper BJ;Frey SH
来自局灶性脑损伤和功能神经成像研究的数据表明，人类左脑顶叶-额叶-颞区的分布网络在有意义的动作(Prxis)的表征中发挥着不同的作用。由于这些数据主要来自惯用右手的人，左脑对实践表征的专门化和手的优势之间的关系仍然不清楚。我们使用功能磁共振成像(FMRI)来评估这一假说，即强烈左撇子(右半球运动占优势)的成年人也表现出这种左脑特化。受试者计划用左手或右手对及物性动作词(如“敲打”)或非及物性动作词(如“挥手”)做出熟悉的动作。在语言控制试验中，线索表示非物理行为(例如，“相信”)。行动计划与左侧边缘上回(SMG)活动的显著、单侧和广泛增加以及左侧尾侧颞中回(CMTg)的局灶性调制有关。这种活动不依赖于手和手势，也就是说，不受参与后续动作表演的手和手势类型(即及物性或不及物性)的影响。与右利手者相比，左利手者右角回(Ang)和背侧运动前皮质(DPMC)的受累程度更高，这表明实践表征的功能结构不那么不对称。因此，我们得出结论，参与计划熟悉动作的机制的组织受到一个人的运动优势的影响。然而，与手的支配地位无关，左侧的SMG和CMTG专门进行观念运动转换--将概念性知识和运动表征整合成有意义的动作。这些发现支持这样的观点，即较高级别的实践表征和较低水平的运动优势依赖于分离机制。
Data from focal brain injury and functional neuroimaging studies implicate a distributed network of parieto-fronto-temporal areas in the human left cerebral hemisphere as playing distinct roles in the representation of meaningful actions (praxis). Because these data come primarily from right-handed individuals, the relationship between left cerebral specialization for praxis representation and hand dominance remains unclear. We used functional magnetic resonance imaging (fMRI) to evaluate the hypothesis that strongly left-handed (right hemisphere motor dominant) adults also exhibit this left cerebral specialization. Participants planned familiar actions for subsequent performance with the left or right hand in response to transitive (e.g., “pounding”) or intransitive (e.g. “waving”) action words. In linguistic control trials, cues denoted non-physical actions (e.g., “believing”). Action planning was associated with significant, exclusively left-lateralized and extensive increases of activity in the supramarginal gyrus (SMg), and more focal modulations in the left caudal middle temporal gyrus (cMTg). This activity was hand- and gesture-independent, i.e., unaffected by the hand involved in subsequent action performance, and the type of gesture (i.e., transitive or intransitive). Compared directly with right-handers, left-handers exhibited greater involvement of the right angular gyrus (ANg) and dorsal premotor cortex (dPMC), which is indicative of a less asymmetric functional architecture for praxis representation. We therefore conclude that the organization of mechanisms involved in planning familiar actions is influenced by one’s motor dominance. However, independent of hand dominance, the left SMg and cMTg are specialized for ideomotor transformations—the integration of conceptual knowledge and motor representations into meaningful actions. These findings support the view that higher-order praxis representation and lower-level motor dominance rely on dissociable mechanisms.
登录
查看更多内容
影响因子：
2
作者：
Choi, SH;Na, DL;Na, DG
通讯作者：
Na, DG
DOI：
10.1044/jshd.4402.156
发表时间：
1979-01-01
期刊：
JOURNAL OF SPEECH AND HEARING DISORDERS
影响因子：
--
作者：
DUFFY, RJ;LILES, BZ
通讯作者：
LILES, BZ
影响因子：
5.7
作者：
Beckmann, CF;Jenkinson, M;Smith, SM
通讯作者：
Smith, SM
影响因子：
0.5
作者：
Buckingham, Hugh W.;Christman, Sarah S.
通讯作者：
Christman, Sarah S.
DOI：
10.1016/0926-6410(95)00034-8
发表时间：
1996-03-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Goldenberg, G;Hermsdorfer, J;Spatt, J
通讯作者：
Spatt, J