Insomnia in untreated sleep apnea patients compared to controls.
Insomnia in untreated sleep apnea patients compared to controls.
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DOI：
10.1111/j.1365-2869.2011.00972.x
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发表时间：
2012-04
影响因子：
4.4
通讯作者：
Benediktsdóttir B
中科院分区：
文献类型：
--
作者：
Björnsdóttir E;Janson C;Gíslason T;Sigurdsson JF;Pack AI;Gehrman P;Benediktsdóttir B
失眠和阻塞性睡眠呼吸暂停 (OSA) 通常同时存在，但其关系的性质尚不清楚。本研究的目的是比较 OSA 患者与普通人群对照组的初期和中期失眠患病率，并研究失眠对 OSA 患者嗜睡和生活质量的影响。对两组未经治疗的 OSA 患者 (n=824) 和来自冰岛普通人群 ≥ 40 岁的对照组 (n=762) 进行了比较。所有受试者都回答了相同的健康和睡眠问卷，OSA 患者接受了睡眠研究。总体而言，53% 的对照者是男性，而 OSA 患者的这一比例为 81%。与一般人群相比，患有 OSA 的男性和女性中，维持睡眠困难 (DMS) 更为常见（分别为 52% 对 31% 和 62% 对 31%，p<0.0001）。与没有 OSA 的女性相比，患有 OSA 的女性更常见入睡困难 (DIS) 和 DIS+DMS。患有 DMS 的 OSA 患者比没有 DMS 的患者更困（Epworth 嗜睡量表：12.2 vs. 10.9，<0.001），而根据简表 12 测量，DMS 和 DIS 都与 OSA 患者较低的生活质量相关（身体评分 39 vs. 42，心理评分 36 vs. 41，p<0.001）。 DIS 和 DMS 与 OSA 严重程度无关。失眠在 OSA 患者中很常见，并且对该患者群体的生活质量和嗜睡产生负面影响。它与 OSA 患者的失眠筛查以及两种情况同时发生时的治疗相关。
Insomnia and obstructive sleep apnea (OSA) often co-exist, but the nature of their relationship is unclear. The aims of this study were to compare the prevalence of initial and middle insomnia between OSA patients and controls from the general population as well as to study the influence of insomnia on sleepiness and quality of life in OSA patients. Two groups were compared, untreated OSA patients (n=824) and controls ≥ 40 years from the general population in Iceland (n=762). All subjects answered the same questionnaires on health and sleep and OSA patients underwent a sleep study. Altogether, 53% of controls were males compared to 81% of OSA patients. Difficulties maintaining sleep (DMS) were more common among men and women with OSA compared to the general population (52 vs. 31% and 62 vs. 31%, respectively, p<0.0001). Difficulties initiating sleep (DIS) and DIS+DMS were more common among women with OSA compared to women without OSA. OSA patients with DMS were sleepier than patients without DMS (Epworth Sleepiness Scale: 12.2 vs. 10.9, <0.001) while both DMS and DIS were related to lower quality of life in OSA patients as measured by the Short Form 12 (physical score 39 vs. 42 and mental score 36 vs. 41, p<0.001). DIS and DMS were not related to OSA severity. Insomnia is common among OSA patients and has a negative influence on quality of life and sleepiness in this patient group. It is relevant to screen for insomnia among OSA patients and treat both conditions when they co-occur.
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影响因子：
4.8
作者：
Benediktsdottir, Bryndis;Janson, Christer;Gislason, Thorarinn
通讯作者：
Gislason, Thorarinn
影响因子：
--
作者：
KLINK, ME;QUAN, SF;LEBOWITZ, MD
通讯作者：
LEBOWITZ, MD
影响因子：
9.6
作者：
Wickwire, Emerson M.;Collop, Nancy A.
通讯作者：
Collop, Nancy A.
影响因子：
5.6
作者：
JOHNS, MW
通讯作者：
JOHNS, MW
影响因子：
5.6
作者：
LeBlanc, Melanie;Merette, Chantal;Morin, Charles M.
通讯作者：
Morin, Charles M.