A randomized trial to assess the immediate impact of acupuncture on quantitative sensory testing, pain, and functional status.
A randomized trial to assess the immediate impact of acupuncture on quantitative sensory testing, pain, and functional status.
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一项随机试验，旨在评估针灸对定量感觉测试、疼痛和功能状态的直接影响。
DOI：
10.1097/j.pain.0000000000001651
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发表时间：
2019
期刊：
影响因子：
7.4
通讯作者：
Mao,Jianren
中科院分区：
文献类型：
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作者：
Chen,Lucy;Deng,Hao;Houle,Timothy;Zhang,Yi;Ahmed,Shihab;Zhang,Vivian;Sullivan,Shelly;Opalaze,Arissa;Roth,Sarah;Filatava,EvgeniaJen;StClair,Kristan;Vo,Tran;Malarick,Charline;Kim,Hyangin;You,Zerong;Shen,Shiqian;Mao,Jianren
在这项随机临床试验中，我们通过分析慢性疼痛参与者的定量感觉测试（QST）曲线，检查了真正的针灸效果是否可以与假针灸（疼痛和功能）区分开来。我们招募了254名健康或慢性背部和颈部疼痛的参与者。纳入健康受试者以控制针灸对基线QST变化的可能影响。研究参与者接受了6次（每周两次）真针灸，假针灸或无针灸治疗（常规护理）。在基线（访视1）和3次（访视4）或6次（访视7）后获得定量感觉测试特征、疼痛评分和功能特征。共分析了204名参与者。我们发现，无论是健康或慢性疼痛的参与者之间的3组（P5 0.533和P5 0.549，似然比检验）QST配置文件的变化。在慢性背部和颈部疼痛的参与者中，真正的针灸减少了疼痛（访视4：平均值差异[DIM] 5 20.8，95%置信区间[CI]：21.4 - 20.1，校正后P 5 0.168;访视7：DIM 5 21.0，95% CI：21.7至20.3，调整后的P 5 0.021）和改善的功能状态，包括身体功能（DIM 5 14.21，95% CI：5.84-22.58，调整后的P 5 0.003）和能量/疲劳（DIM 5 12.28，95% CI：3.46-21.11，调整后的P 5 0.021）。我们的研究结果表明，QST是没有帮助区分真正的针灸和假针灸（主要结果）在这项研究中，虽然真正的针灸减少疼痛和改善功能（次要结果）相比，常规护理。
In this randomized clinical trial, we examined whether the effect of true acupuncture can be differentiated from sham acupuncture (pain and functionality) by analyzing quantitative sensory testing (QST) profiles in chronic pain participants. We recruited 254 healthy or chronic back and neck pain participants. Healthy subjects were included to control for a possible effect of acupuncture on baseline QST changes. Study participants received 6 sessions (twice weekly) of true acupuncture, sham acupuncture, or no acupuncture treatment (routine care). Quantitative sensory testing profiles, pain scores, and functionality profile were obtained at baseline (visit 1) and after 3 (visit 4) or 6 sessions (visit 7). A total of 204 participants were analyzed. We found no QST profile changes among 3 groups (P 5 0.533 and P 5 0.549, likelihood ratio tests) in either healthy or chronic pain participants. In chronic back and neck pain participants, true acupuncture reduced pain (visit 4: difference in mean [DIM] 5 20.8, 95% confidence interval [CI]: 21.4 to 20.1, adjusted P 5 0.168; visit 7: DIM 5 21.0, 95% CI: 21.7 to 20.3, adjusted P 5 0.021) and improved functional status including physical functioning (DIM 5 14.21, 95% CI: 5.84-22.58, adjusted P 5 0.003) and energy/fatigue (DIM 5 12.28, 95% CI: 3.46-21.11, adjusted P 5 0.021) as compared to routine care. Our results indicate that QST was not helpful to differentiate between true acupuncture and sham acupuncture (primary outcome) in this study, although true acupuncture reduced pain and improved functionality (secondary outcomes) when compared with routine care.
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影响因子：
7.4
作者：
Chen L;Malarick C;Seefeld L;Wang S;Houghton M;Mao J
通讯作者：
Mao J
激光针刺激前后性别特异性热感觉和疼痛阈值的定量 Bestimmung geschlechtsspezifischer Empfindungs- und Schmerzschwellen vor und nach Lasernedelstimulation / Quantification of Gender Specific Thermal Sensory and Pain Threshold Before and After Laserneedle Stimulation
DOI：
10.1515/bmt.2004.022
发表时间：
2004
期刊：
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie
影响因子：
--
作者：
G. Litscher;L. Wang;E. Huber;D. Schikora;G. Schwarz
通讯作者：
G. Schwarz
影响因子：
120.7
作者：
Boutron, I;Tubach, F;Ravaud, P
通讯作者：
Ravaud, P
DOI：
10.1007/s00132-002-0339-4
发表时间：
2002
期刊：
Der Orthopäde
影响因子：
--
作者：
A. Molsberger;G. Böwing;M. Haake;U. Meier;J. Winkler;F. Molsberger
通讯作者：
F. Molsberger
影响因子：
5.7
作者：
Lang, Philip M.;Stoer, Johanna;Irnich, Dominik
通讯作者：
Irnich, Dominik