Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos.
Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos.
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DOI：
10.1001/jamanetworkopen.2022.21982
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发表时间：
2022-07-01
影响因子：
13.8
通讯作者：
Testai, Fernando D.
中科院分区：
文献类型：
--
作者：
Moustafa, Bayan;Trifan, Gabriela;Isasi, Carmen R.;Lipton, Richard B.;Sotres-Alvarez, Daniela;Cai, Jianwen;Tarraf, Wassim;Stickel, Ariana;Mattei, Josiemer;Talavera, Gregory A.;Daviglus, Martha L.;Gonzalez, Hector M.;Testai, Fernando D.
这项队列研究评估了西班牙社区健康研究/拉丁裔研究和拉丁裔研究——神经认知衰老研究参与者中报告的地中海饮食类型食品和饮料的消费量与认知表现变化之间的关系。地中海饮食与不同西班牙裔或拉丁裔成年人认知能力下降的减少有关吗？在这项针对 6321 名西班牙裔或拉丁裔成年人的队列研究中，与低水平坚持地中海饮食相比，高水平坚持地中海饮食与更好的整体认知以及减少 7 年学习和记忆衰退有关。研究结果表明，食用适合文化的地中海饮食可能会降低西班牙裔或拉丁裔中老年人认知能力下降和阿尔茨海默病的风险。地中海饮食可以减轻西班牙裔或拉丁裔人群阿尔茨海默病和其他相关痴呆症的负担。调查地中海饮食与社区居住的西班牙裔或拉丁裔成年人认知表现的关系。这项队列研究分析了西班牙裔社区健康研究/拉丁裔研究 (HCHS/SOL) 和拉丁裔研究 - 神经认知衰老调查 (SOL-INCA)（一项 HCHS/SOL 辅助研究）的数据。 2008年3月至2011年6月（访问1）在HCHS/SOL中进行了认知测试，2015年10月至2018年3月（访问2）在SOL-INCA中进行了认知测试。本研究中的参与者在第 1 次访视时完成了饮食评估，在第 1 次和第 2 次访视时完成了神经认知评估。数据分析时间为 2021 年 9 月至 2022 年 5 月。使用地中海饮食评分 (MDS) 确定地中海饮食依从性，分为低（MDS：0-4 分）、中（MDS：5-6 分）或高（MDS：7-9 分）。使用两次 24 小时饮食回忆的平均值来计算 MDS。就诊 1 和 2 之间的认知变化是通过从就诊 1 时的认知得分减去就诊 2 时的认知得分并根据就诊之间经过的时间和就诊 1 时的认知得分进行调整来计算的。神经认知测试包括简短的西班牙语-英语言语学习测试 (B-SEVLT) 总和、B-SEVLT 回忆、单词流利度和数字符号替换测试 (DSST)。每项测试的结果均经过 z 分数转换，并对平均值进行平均以创建全局认知分数。使用复杂样本线性回归分析来确定 MDS 与每次就诊时的神经认知表现和神经认知变化之间的关联。共有 6321 名参与者（平均 [SE] 年龄，第 1 次访视时 56.1 [0.18] 岁；n = 4077 名女性 [57.8%]）被纳入。低依从性组的地中海饮食依从权重频率为35.8%（6321人中n = 2112人），中度依从性组为45.4%（n = 2795人），高依从性组为18.8%（n = 1414人）。在完全调整的模型中，高依从性组与低依从性组在第 1 次访视时的 z 得分转换认知得分较高：B-SEVLT Sum（β = 0.11；95% CI，0.02-0.20）、B-SEVLT Recall（β = 0.16；95% CI，0.07-0.25）和整体认知（β = 0.10；95% CI，0.04-0.16）测试。在 7 年的平均随访时间内，高依从性组与低依从性组在 B-SEVLT Sum（β = 0.12；95% CI，0.05-0.20）和 B-SEVLT Recall（β = 0.14；95% CI，0.05-0.23）方面的认知变化不太明显，但在单词流利度、DSST 评分或总体评分方面则不明显。认知得分。这项队列研究的结果表明，高度坚持地中海饮食与中年和老年西班牙裔或拉丁裔成年人更好的认知表现以及减少 7 年学习和记忆衰退有关。根据文化定制的地中海饮食可能会降低该人群认知能力下降和阿尔茨海默病的风险。
This cohort study evaluates the association of reported consumption of Mediterranean-diet types of foods and beverages with cognitive performance changes among participants in the Hispanic Community Health Study/Study of Latinos and the Study of Latinos–Investigation of Neurocognitive Aging. Is a Mediterranean diet associated with reduced cognitive decline among diverse Hispanic or Latino adults? In this cohort study of 6321 Hispanic or Latino adults, a high level of adherence to the Mediterranean diet was associated with better global cognition and decreased 7-year learning and memory decline compared with a low level of adherence to the diet. Findings suggest that consumption of a culturally tailored Mediterranean diet may reduce the risk of cognitive decline and Alzheimer disease among middle-aged and older adults with Hispanic or Latino ethnicity. The Mediterranean diet may reduce the burden of Alzheimer disease and other associated dementias in Hispanic or Latino people. To investigate the association of a Mediterranean diet with cognitive performance among community-dwelling Hispanic or Latino adults. This cohort study analyzed data from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and the Study of Latinos–Investigation of Neurocognitive Aging (SOL–INCA), an HCHS/SOL ancillary study. Cognition tests were administered in the HCHS/SOL from March 2008 to June 2011 (visit 1) and in the SOL–INCA from October 2015 to March 2018 (visit 2). Participants included in the present study had completed a diet assessment at visit 1 and neurocognitive evaluations at visits 1 and 2. Data were analyzed from September 2021 to May 2022. Mediterranean diet adherence was ascertained using the Mediterranean diet score (MDS) and was categorized as low (MDS: 0-4 points), moderate (MDS: 5-6 points), or high (MDS: 7-9 points). The mean of two 24-hour dietary recalls was used to calculate the MDS. Cognitive change between visits 1 and 2 was calculated by subtracting the cognitive score at visit 2 from the cognitive score at visit 1 and adjusting by the time elapsed between visits and cognitive score at visit 1. Neurocognitive tests administered were Brief Spanish-English Verbal Learning Test (B-SEVLT) Sum, B-SEVLT Recall, word fluency, and Digit Symbol Substitution Test (DSST). Results of each test were z score–transformed and the means were averaged to create a global cognition score. Complex sample linear regression analysis was used to ascertain the association between MDS and neurocognitive performance at each visit and neurocognitive change. A total of 6321 participants (mean [SE] age, 56.1 [0.18] years at visit 1; n = 4077 women [57.8%]) were included. Mediterranean diet adherence weighted frequencies were 35.8% (n = 2112 of 6321) for the low adherence group, 45.4% (n = 2795) for the moderate adherence group, and 18.8% (n = 1414) for the high adherence group. In the fully adjusted model, z score–transformed cognitive scores at visit 1 in the high vs low adherence groups were higher for B-SEVLT Sum (β = 0.11; 95% CI, 0.02-0.20), B-SEVLT Recall (β = 0.16; 95% CI, 0.07-0.25), and global cognition (β = 0.10; 95% CI, 0.04-0.16) tests. In the mean follow-up time of 7 years, cognitive change in the high vs low adherence groups was less pronounced for B-SEVLT Sum (β = 0.12; 95% CI, 0.05-0.20) and B-SEVLT Recall (β = 0.14; 95% CI, 0.05-0.23), but not for word fluency, DSST score, or global cognition score. Results of this cohort study suggested that high adherence to a Mediterranean diet was associated with better cognitive performance and decreased 7-year learning and memory decline among middle-aged and older Hispanic or Latino adults. Culturally tailored Mediterranean diet may reduce the risk of cognitive decline and Alzheimer disease in this population.
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影响因子：
9.9
作者：
Tsivgoulis, Georgios;Judd, Suzanne;Wadley, Virginia G.
通讯作者：
Wadley, Virginia G.
影响因子：
5.6
作者：
Sorlie, Paul D.;Aviles-Santa, Larissa M.;Wassertheil-Smoller, Sylvia;Kaplan, Robert C.;Daviglus, Martha L.;Giachello, Aida L.;Schneiderman, Neil;Raij, Leopoldo;Talavera, Gregory;Allison, Matthew;Lavange, Lisa;Chambless, Lloyd E.;Heiss, Gerardo
通讯作者：
Heiss, Gerardo
地中海饮食与轻度认知障碍与阿尔茨海默氏病的关联：系统评价和荟萃分析。
DOI：
10.3233/jad-130830
发表时间：
2014
期刊：
Journal of Alzheimer's disease : JAD
影响因子：
--
作者：
Singh B;Parsaik AK;Mielke MM;Erwin PJ;Knopman DS;Petersen RC;Roberts RO
通讯作者：
Roberts RO
影响因子：
9.9
作者：
Ballarini, Tommaso;van Lent, Debora Melo;Wagner, Michael
通讯作者：
Wagner, Michael
影响因子：
14
作者：
Gonzalez, Hector M.;Tarraf, Wassim;Schneiderman, Neil
通讯作者：
Schneiderman, Neil