Pituitary-ovary-spleen axis in ovulation.

Pituitary-ovary-spleen axis in ovulation.
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DOI:
10.1016/j.tem.2011.04.005
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发表时间:
2011-09
影响因子:
10.9
通讯作者:
Ko, CheMyong
Ko, CheMyong
中科院分区:
医学1区
文献类型:
--
作者:
Oakley, Oliver R.;Frazer, Michele L.;Ko, CheMyong

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Leukocytes are rapidly recruited to the preovulatory ovary and play a crucial role as facilitators of ovulation and luteal formation. In this article, recent findings on leukocyte trafficking to the ovary, as well as the physiological role of leukocytes in the ovary, will be summarized and discussed. We then explore the novel hypothesis that the hypothalamus-pituitary-ovarian (HPO) axis might include the spleen as a reservoir of leukocytes by summarizing recent reports on this topic, both in the fields of immunology and reproductive biology.
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