CT scans in sub-groups of chronic schizophrenics.
CT scans in sub-groups of chronic schizophrenics.
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慢性精神分裂症亚组的 CT 扫描。
DOI：
10.1016/0022-3956(82)90042-5
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发表时间：
1982
影响因子：
4.8
通讯作者：
A. Orzeck
中科院分区：
文献类型：
--
作者：
A. Kling;N. Kurtz;K. Tachiki;A. Orzeck
测量了26例慢性精神分裂症患者、22例酒精中毒和神经系统疾病患者和20例正常对照者的脑室脑比率（VBR）、侧裂宽度和额叶对称性。所有精神分裂症患者均对3-25年的长期抗精神病药物治疗无反应，年龄在23 - 45岁之间。详细的诊断工作区分两个亚组DSM III标准，残留和偏执。前一组的特点是大的VBR，而偏执狂的范围内正常对照。VBR大于9的患者大脑外侧裂较宽，额叶反向不对称的频率增加。作为一个群体，所有精神分裂症患者的VBR与正常对照组有显著差异，但与酗酒者或神经系统疾病（偏头痛、全身性癫痫发作）患者的VBR没有差异。这一发现表明，DSM III标准适用于CT扫描措施可能有助于定义一个亚组内的精神分裂症。虽然不是特定于这种疾病，潜在的病理表现出增加的VBR和其他CT扫描的变化可能是特定的，但不同于其他疾病。
Measurements of the ventricular brain ratio (VBR), width of the sylvian fissure, and symmetry of the frontal lobes were obtained from 26 chronic schizophrenic patients, 22 alcoholic and neurological patients, and 20 normal controls. All schizophrenic subjects were non-responsive to long-term neuroleptic medication for 3–25 yr and were between 23 and 45 yr of age. Detailed diagnostic workups differentiated two sub-groups by DSM III criteria, residual and paranoid. The former group was characterized by large VBRs while the paranoids were within the range of normal controls. Those patients with VBRs greater than nine had wider sylvian fissures and increased frequency of reversed frontal asymmetry. As a group, the VBRs of all schizophrenics differed significantly from normal controls but did not differ from those of alcoholics or patients with neurological disorders (migraine, generalized seizures). This finding indicates that DSM III criteria applied to CT scan measures may help define a sub-group within the schizophrenias.While not specific to this disorder, the underlying pathology demonstrating increased VBRs and other CT scan changes may be specific to but different from other disorders.
DOI：
10.1176/ajp.139.4.427
发表时间：
1982-04
期刊：
The American journal of psychiatry
影响因子：
--
作者：
N. Andreasen;J. Dennert;S. Olsen;A. Damasio
通讯作者：
N. Andreasen;J. Dennert;S. Olsen;A. Damasio
精神分裂症的心室扩大：与阳性和阴性症状的关系。
DOI：
10.1176/ajp.139.3.297
发表时间：
1982
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Andreasen,NC;Olsen,SA;Dennert,JW;Smith,MR
通讯作者：
Smith,MR