Ventricular enlargement in schizophrenia: relationship to positive and negative symptoms.
Ventricular enlargement in schizophrenia: relationship to positive and negative symptoms.
复制标题
精神分裂症的心室扩大:与阳性和阴性症状的关系。
DOI:
10.1176/ajp.139.3.297
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发表时间:
1982
期刊:
影响因子:
--
通讯作者:
Smith,MR
中科院分区:
文献类型:
--
作者:
Andreasen,NC;Olsen,SA;Dennert,JW;Smith,MR
The authors explored the clinical correlates of ventricular enlargement in schizophrenia by comparing 16 patients with" large" ventricles (ventricles more than I SD above the control mean) with 16 patients with the smallest ventricles from a sample of 52 schizophrenic patients. Patients with ventricular enlargement showed some impairment in the sensorium and had a preponderance of" negative" symptoms (eg, alogia, affective flattening, avolition, anhedonia), while those with small ventricles were characterized by" positive" symptoms (eg, delusions, hallucinations, positive formal thought disorder, bizarre behavior). These findings suggest that combining a measure of brain structure with the clinical picture may provide a useful new approach to the classification of schizophrenia.
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