Kathryn V. Holmes: A Career of Contributions to the Coronavirus Field.

Kathryn V. Holmes: A Career of Contributions to the Coronavirus Field.
复制标题

DOI:
10.3390/v14071573
复制
发表时间:
2022-07-20
期刊:
Viruses
影响因子:
--
通讯作者:
--
中科院分区:
其他
文献类型:
--
作者:

文献摘要

参考文献

相似文献

在过去两年中,科学研究以前所未有的速度应对COVID-19大流行。如果没有包括凯瑟琳·霍姆斯(Kathryn Holmes)在内的研究人员数十年来对冠状病毒的广泛背景知识,有效疫苗和治疗方法的快速开发是不可能的。Kay的研究团队发现了小鼠肝炎病毒和人类冠状病毒229 E的第一个冠状病毒受体,并为冠状病毒刺突糖蛋白和受体相互作用提供了丰富的信息,这些信息是宿主和组织特异性的关键决定因素。她与几个研究实验室合作,在其他领域贡献知识,包括冠状病毒的发病机制,流行病学和进化。在她的整个职业生涯中,凯是一个非常敬业和周到的导师,许多研究生和博士后研究员。本文回顾了她对冠状病毒领域的贡献以及她的模范指导。
Over the past two years, scientific research has moved at an unprecedented rate in response to the COVID-19 pandemic. The rapid development of effective vaccines and therapeutics would not have been possible without extensive background knowledge on coronaviruses developed over decades by researchers, including Kathryn (Kay) Holmes. Kay’s research team discovered the first coronavirus receptors for mouse hepatitis virus and human coronavirus 229E and contributed a wealth of information on coronaviral spike glycoproteins and receptor interactions that are critical determinants of host and tissue specificity. She collaborated with several research laboratories to contribute knowledge in additional areas, including coronaviral pathogenesis, epidemiology, and evolution. Throughout her career, Kay was an extremely dedicated and thoughtful mentor to numerous graduate students and post-doctoral fellows. This article provides a review of her contributions to the coronavirus field and her exemplary mentoring.
DOI: 10.1128/jvi.66.12.7420-7428.1992
发表时间: 1992-12-01
影响因子: 5.4
作者:
COMPTON, SR;STEPHENSEN, CB;HOLMES, KV
通讯作者: HOLMES, KV
DOI: 10.1099/vir.0.044628-0
发表时间: 2012-11-01
影响因子: 3.8
作者:
Dominguez, Samuel R.;Sims, Gregory E.;Holmes, Kathryn V.
通讯作者: Holmes, Kathryn V.
DOI: 10.1128/jvi.69.2.889-895.1995
发表时间: 1995-02-01
影响因子: 5.4
作者:
GAGNETEN, S;GOUT, O;HOLMES, KV
通讯作者: HOLMES, KV
氨基肽酶N是肠道病毒冠状病毒TGEV的主要受体。
DOI: 10.1038/357417a0
发表时间: 1992-06-04
期刊: Nature
影响因子: 64.8
作者:
Delmas B;Gelfi J;L'Haridon R;Vogel LK;Sjöström H;Norén O;Laude H
通讯作者: Laude H
DOI: 10.1083/jcb.109.5.2405
发表时间: 1989-11
期刊: The Journal of cell biology
影响因子: --
作者:
Godfraind C;Friedrich VL;Holmes KV;Dubois-Dalcq M
通讯作者: Dubois-Dalcq M