Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research.
Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research.
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DOI：
10.1167/tvst.11.12.7
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发表时间：
2022-12-01
影响因子：
3
通讯作者：
Kremlacek, Jan
中科院分区：
文献类型：
--
作者：
Kordek, David;Voda, Petr;Young, Laura K.;Kremlacek, Jan
目的：探讨屈光模糊对运动诱发视觉诱发电位(MO-VEP)的影响。对12名受试者进行了中心、周边和全场刺激，测试了高达4D的屈光模糊对MO-VEP的影响，刺激对象为空间频率为1c/°的低对比度同心圆。并与15ʹ和60ʹ棋盘图形反转(PR-VEP)诱发的VEP进行比较。线性回归分析表明，优势成分的峰值时间和峰间波幅与屈光度模糊程度相关。两种棋盘大小的MO-VEP均未表现出明显的峰值延长(P>；0.28)或波幅衰减(P>；0.14)，而PR-VEP的波幅(P<；0.001)显著降低，峰值时间(P<；0.001)明显延长。对于低对比度和低空间频率模式的径向运动诱发的MO-VEP，视网膜模糊的变化不影响主要的N_2成分的峰值时间或峰间幅度。我们为MO-VEP显示的对视网膜模糊的抵抗提供了一个诊断机会来测试视觉系统的完整性，并揭示即使在未经矫正的屈光不正的情况下也存在球后损害。
To describe the effect of dioptric blur on visual evoked potentials (VEPs) induced by motion onset (MO-VEPs). The effect of dioptric blur up to 4 D on MO-VEPs was tested on 12 subjects using central, peripheral, and full-field stimulation with a low-contrast structure of concentric circles with spatial frequency <1 c/°. The results were compared to VEPs evoked by 15ʹ and 60ʹ checkerboard pattern-reversal (PR-VEPs). The relationship between peak time and interpeak amplitude of the dominant components was related to the level of dioptric blur using linear regression. The MO-VEPs did not show a significant peak prolongation (P > 0.28) or amplitude attenuation (P > 0.14) with the blur, whereas for the PR-VEPs we observed a significant decrease in amplitude (P < 0.001) and increase in peak time (P < 0.001) for both checkerboard sizes. For MO-VEPs induced by radial motion of low contrast and low spatial frequency pattern, the change in retinal blur does not affect the peak time or the interpeak amplitude of the dominant N2 component. The resistance to retinal blur that we demonstrated for MO-VEP provides a diagnostic opportunity to test the integrity of the visual system and reveal a retrobulbar impairment even in uncorrected refractive errors.
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影响因子：
5.7
作者：
Di Russo, F;Pitzalis, S;Hillyard, SA
通讯作者：
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影响因子：
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影响因子：
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影响因子：
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作者：
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