Development of at-home sample collection logistics for large-scale seroprevalence studies.
Development of at-home sample collection logistics for large-scale seroprevalence studies.
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DOI：
10.1371/journal.pone.0258516
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Mina MJ
中科院分区：
文献类型：
--
作者：
Aatresh AV;Cummings K;Gerstein H;Knight CS;Limberopolous A;Stasi MA;Bedugnis A;Somberg KA;França CT;Mina MJ
血清学研究依赖于招募具有代表性的队列；然而，由于covid - 19大流行的情况，这些努力特别复杂。我们的目标是设计和实施一种完全远程的方法来进行安全的血清学调查，同时允许有代表性的研究人群参与。这个设计很受欢迎，效果也很好。2066名年龄≥18岁的参与者入选，反映了马萨诸塞州的民族和种族构成。70%的人对在线登记和在家自行采集血样表示满意/非常满意。虽然18.6%的人表示在收集过程中遇到了一些不适，但72.2%的人表示，如果参加长期研究，他们愿意每周进行一次测试。参与者的高度参与和积极反馈，以及自我收集标本的质量，表明这种完全远程、基于自我收集的研究设计对未来更安全、更有效的人群水平血清学调查是有用的。
Serological studies rely on the recruitment of representative cohorts; however, such efforts are specially complicated by the conditions surrounding the COVID19 pandemic. We aimed to design and implement a fully remote methodology for conducting safe serological surveys that also allow for the engagement of representative study populations. This design was well-received and effective. 2,066 participants ≥18 years old were enrolled, reflecting the ethnic and racial composition of Massachusetts. >70% of them reported being satisfied/extremely satisfied with the online enrollment and at-home self-collection of blood samples. While 18.6% reported some discomfort experienced with the collection process, 72.2% stated that they would be willing to test weekly if enrolled in a long-term study. High engagement and positive feedback from participants, as well as the quality of self-collected specimens, point to the usefulness of this fully remote, self-collection-based study design for future safer and efficient population-level serological surveys.
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影响因子：
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作者：
Tai, Don Bambino Geno;Shah, Aditya;Wieland, Mark L.
通讯作者：
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通讯作者：
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