Aptamer based electrochemical sensors for emerging environmental pollutants.

Aptamer based electrochemical sensors for emerging environmental pollutants.
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DOI:
10.3389/fchem.2014.00041
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发表时间:
2014
影响因子:
5.5
通讯作者:
Marty JL
Marty JL
中科院分区:
化学3区
文献类型:
--
作者:
Hayat A;Marty JL

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环境污染物监测是了解和管理对人类健康和生态系统危害的关键问题之一。在这种背景下,基于适体的电化学传感器因其能够解决环境污染中潜在的大量问题和挑战而取得了巨大的意义。适体传感器是一种紧凑的分析装置,将适体(寡核苷酸)作为传感元件集成在生化传感器表面内或与生化传感器表面紧密相关。众所周知,核酸具有携带和传递遗传信息的功能,但近年来,它在分析监测中发挥着关键作用。基于适体的传感器代表了环境分析科学中的一项新颖性,人们对其作为传统分析工具的替代品的良好性能寄予厚望。本综述重点介绍了环境应用中基于适体的电化学传感器的最新进展,特别是新兴污染物。
Environmental contaminants monitoring is one of the key issues in understanding and managing hazards to human health and ecosystems. In this context, aptamer based electrochemical sensors have achieved intense significance because of their capability to resolve a potentially large number of problems and challenges in environmental contamination. An aptasensor is a compact analytical device incorporating an aptamer (oligonulceotide) as the sensing element either integrated within or intimately associated with a physiochemical transducer surface. Nucleic acid is well known for the function of carrying and passing genetic information, however, it has found a key role in analytical monitoring during recent years. Aptamer based sensors represent a novelty in environmental analytical science and there are great expectations for their promising performance as alternative to conventional analytical tools. This review paper focuses on the recent advances in the development of aptamer based electrochemical sensors for environmental applications with special emphasis on emerging pollutants.
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