Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1).
Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1).
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野鸭作为高度致病的鸟类流感病毒（H5N1）的长距离载体。
DOI：
10.3201/eid1404.071016
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发表时间：
2008-04
影响因子：
11.8
通讯作者：
Kuiken, Thijs
中科院分区：
文献类型：
--
作者：
Keawcharoen, Julthatip;van Riel, Debby;van Amerongen, Geert;Bestebroer, Theo;Beyer, Walter E.;van Lavieren, Rob;Osterhaus, Albert D. M. E.;Fouchier, Ron A. M.;Kuiken, Thijs
有些鸭类是潜在的远距离传播媒介;其他的则更有可能充当哨兵。野鸟与高致病性禽流感病毒（H5 N1）在亚洲、中东、欧洲和非洲爆发的扩大有关（除了通过受感染的家禽、受污染的设备和人的传统传播之外）。这种作用需要野鸟在没有使人衰弱的疾病的情况下排泄病毒。通过实验感染野鸭，我们发现簇绒鸭、欧亚野鸭和绿头鸭比普通野鸭、欧亚野鸭和牛虻排出的病毒明显更多;然而只有簇绒鸭和程度较轻的野鸭生病或死亡。这些发现表明，一些野鸭物种，特别是野鸭，可能是高致病性禽流感病毒（H5 N1）的远距离传播媒介，而其他物种，特别是簇绒鸭，更有可能充当哨兵。
Some duck species are potential long-distance vectors; others are more likely to function as sentinels. Wild birds have been implicated in the expansion of highly pathogenic avian influenza virus (H5N1) outbreaks across Asia, the Middle East, Europe, and Africa (in addition to traditional transmission by infected poultry, contaminated equipment, and people). Such a role would require wild birds to excrete virus in the absence of debilitating disease. By experimentally infecting wild ducks, we found that tufted ducks, Eurasian pochards, and mallards excreted significantly more virus than common teals, Eurasian wigeons, and gadwalls; yet only tufted ducks and, to a lesser degree, pochards became ill or died. These findings suggest that some wild duck species, particularly mallards, can potentially be long-distance vectors of highly pathogenic avian influenza virus (H5N1) and that others, particularly tufted ducks, are more likely to act as sentinels.
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影响因子：
11.8
作者：
Brown JD;Stallknecht DE;Beck JR;Suarez DL;Swayne DE
通讯作者：
Swayne DE
影响因子：
3.3
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影响因子：
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影响因子：
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作者：
Sturm-Ramirez, KM;Hulse-Post, DJ;Webster, RG
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