Inevitability of the emergence and persistence of genetic parasites caused by evolutionary instability of parasite-free states.

Inevitability of the emergence and persistence of genetic parasites caused by evolutionary instability of parasite-free states.
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DOI:
10.1186/s13062-017-0202-5
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发表时间:
2017-12-04
期刊:
影响因子:
5.5
通讯作者:
Katsnelson MI
Katsnelson MI
中科院分区:
生物学2区
文献类型:
--
作者:
Koonin EV;Wolf YI;Katsnelson MI

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遗传寄生虫,包括病毒和移动的遗传元件,在细胞生命形式中普遍存在,并且是地球上最丰富的生物实体,具有大部分的遗传多样性。在这里,我们检查简单的思想实验来证明,无论是在简单的复制系统中的寄生虫的出现和它们的持久性在进化的生命形式是不可避免的,因为假定的寄生虫免费状态是进化不稳定的。本文已由Yitzhak Pilpel、Bojan Zagrovic和Eric货车Nimwegen审阅。
Genetic parasites, including viruses and mobile genetic elements, are ubiquitous among cellular life forms, and moreover, are the most abundant biological entities on earth that harbor the bulk of the genetic diversity. Here we examine simple thought experiments to demonstrate that both the emergence of parasites in simple replicator systems and their persistence in evolving life forms are inevitable because the putative parasite-free states are evolutionarily unstable. This article has been reviewed by Yitzhak Pilpel, Bojan Zagrovic, and Eric van Nimwegen.
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