Resilience and efficiency for the nanotechnology supply chains underpinning COVID-19 vaccine development.
Resilience and efficiency for the nanotechnology supply chains underpinning COVID-19 vaccine development.
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DOI：
10.1016/j.coche.2021.100759
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发表时间：
2021-12
影响因子：
6.6
通讯作者：
Linkov I
中科院分区：
文献类型：
--
作者：
Golan MS;Mahoney E;Trump B;Linkov I
纳米技术促进了许多SARS-CoV-2疫苗的开发和规模化商业化。然而，支撑疫苗生产的供应链在开发和分销的各个阶段都表现出脆弱性。虽然这种脆弱性使更广泛的药物供应链容易受到重大和不可接受的破坏，但政府，学术界和工业界正在考虑供应链弹性战略。然而，如何理解和参数化这种弹性是有争议的。我们的审查纳米技术供应链弹性的文献，合成与较大的供应链弹性的文献，分析目前的趋势，在实施和建模的弹性和建议弥合差距缺乏定量模型，一致的定义，和权衡分析纳米供应链。
Nanotechnology facilitated the development and scalable commercialization of many SARS-CoV-2 vaccines. However, the supply chains underpinning vaccine manufacturing have demonstrated brittleness at various stages of development and distribution. Whereas such brittleness leaves the broader pharmacological supply chain vulnerable to significant and unacceptable disruption, strategies for supply chain resilience are being considered across government, academia, and industry. How such resilience is understood and parameterized, however, is contentious. Our review of the nanotechnology supply chain resilience literature, synthesized with the larger supply chain resilience literature, analyzes current trends in implementing and modeling resilience and recommendations for bridging the gap in the lack of quantitative models, consistent definitions, and trade-off analyses for nano supply chains.
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影响因子：
7.8
作者：
Buschmann MD;Carrasco MJ;Alishetty S;Paige M;Alameh MG;Weissman D
通讯作者：
Weissman D
影响因子：
7.3
作者：
Goel, Saurav;Hawi, Sara;Barber, Asa H.
通讯作者：
Barber, Asa H.
影响因子：
4.9
作者：
Jimenez, Araceli Sanchez;Puelles, Raquel;Llopis, Isabel Rodriguez
通讯作者：
Llopis, Isabel Rodriguez
影响因子：
5.7
作者：
Schmutz, Melanie;Borges, Olga;Som, Claudia
通讯作者：
Som, Claudia
影响因子：
4.9
作者：
Soeteman-Hernandez, Lya G.;Sutcliffe, Hilary R.;Sips, Adrienne J. A. M.
通讯作者：
Sips, Adrienne J. A. M.