Nosocomial pneumonia: pathogenesis and recent advances in diagnosis and therapy.
Nosocomial pneumonia: pathogenesis and recent advances in diagnosis and therapy.
复制标题
院内肺炎:发病机制及诊断和治疗的最新进展。
DOI:
--
复制
发表时间:
1991
期刊:
影响因子:
--
通讯作者:
G. Mandell
中科院分区:
文献类型:
--
作者:
W. Scheld;G. Mandell
Despite recent progress in the prevention and treatment of hospital-acquired infections, nosocomial pneumonia remains an important problem among critically ill patients. Nosocomial pneumonia develops in five to 10 patients per 1,000 admissions and has a mortality rate of 20%-50%. This review focuses on three areas of nosocomial pneumonia that have been the subject of investigation in recent years: (1) pathogenesis, especially the role of gastric colonization with gram-negative bacilli in retrograde pharyngeal spread; (2) diagnosis, particularly by means of bronchoalveolar lavage and the protected specimen brush during bronchoscopy; and (3) therapy with extended-spectrum penicillins, third-generation cephalosporins, imipenem, aztreonam, and quinolones.
DOI:
10.1172/jci110395
发表时间:
1981
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Woods,DE;Straus,DC;JohansonJr,WG;Bass,JA
通讯作者:
Bass,JA
影响因子:
6.4
作者:
THORPE, JE;BAUGHMAN, RP;STANECK, JL
通讯作者:
STANECK, JL
DOI:
10.1164/arrd.1982.125.1.53
发表时间:
1982
期刊:
The American review of respiratory disease
影响因子:
--
作者:
Higuchi,JH;Coalson,JJ;JohansonJr,WG
通讯作者:
JohansonJr,WG