A new shield for a cytokine storm.

A new shield for a cytokine storm.
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DOI:
10.1016/j.cell.2011.08.027
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发表时间:
2011-09-16
期刊:
影响因子:
64.5
通讯作者:
Medzhitov R
Medzhitov R
中科院分区:
生物学1区
文献类型:
--
作者:
Iwasaki A;Medzhitov R

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Highly virulent influenza virus infection results in excessive cytokine production, recruitment of leukocytes and immune-mediated pulmonary injury. now demonstrate that sphingosine 1 phosphate receptor 1 ligands suppress all features of flu-inflicted pathological inflammation and places the endothelium at the center of this regulatory network.
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