Computational methods for protein localization prediction.
Computational methods for protein localization prediction.
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DOI:
10.1016/j.csbj.2021.10.023
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发表时间:
2021
影响因子:
6
通讯作者:
Xu D
中科院分区:
文献类型:
--
作者:
Jiang Y;Wang D;Wang W;Xu D
The accurate annotation of protein localization is crucial in understanding protein function in tandem with a broad range of applications such as pathological analysis and drug design. Since most proteins do not have experimentally-determined localization information, the computational prediction of protein localization has been an active research area for more than two decades. In particular, recent machine-learning advancements have fueled the development of new methods in protein localization prediction. In this review paper, we first categorize the main features and algorithms used for protein localization prediction. Then, we summarize a list of protein localization prediction tools in terms of their coverage, characteristics, and accessibility to help users find suitable tools based on their needs. Next, we evaluate some of these tools on a benchmark dataset. Finally, we provide an outlook on the future exploration of protein localization methods.
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影响因子:
14.9
作者:
Lee, KiYoung;Kim, Dae-Won;Na, DoKyun;Lee, Kwang H.;Lee, Doheon
通讯作者:
Lee, Doheon
影响因子:
16.6
作者:
Christoforou A;Mulvey CM;Breckels LM;Geladaki A;Hurrell T;Hayward PC;Naake T;Gatto L;Viner R;Martinez Arias A;Lilley KS
通讯作者:
Lilley KS
影响因子:
3
作者:
Blum T;Briesemeister S;Kohlbacher O
通讯作者:
Kohlbacher O
影响因子:
14.9
作者:
Briesemeister S;Rahnenführer J;Kohlbacher O
通讯作者:
Kohlbacher O
DOI:
10.1093/protein/12.2.107
发表时间:
1999-02-01
期刊:
PROTEIN ENGINEERING
影响因子:
--
作者:
Chou, KC;Elrod, DW
通讯作者:
Elrod, DW