Nonphotic Entrainment in a Diurnal Mammal, the European Ground Squirrel (Spermophilus citellus)
Nonphotic Entrainment in a Diurnal Mammal, the European Ground Squirrel (Spermophilus citellus)
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昼夜哺乳动物欧洲地松鼠（Spermophilus citellus）的非光夹带
DOI：
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发表时间：
1999
影响因子：
3.5
通讯作者：
S. Daan
中科院分区：
文献类型：
--
作者：
R. Hut;N. Mrosovsky;S. Daan
在夜间活动的啮齿动物中，已经详细研究了非光性活动诱导刺激的夹带作用，但对白天动物的非光性夹带作用知之甚少。比较研究将提供区分两种可能性的机会。(1)如果非光相移取决于活动周期的相位，则夜间和昼夜活动的哺乳动物的相位响应曲线(PRC)应相差约180°。(2)如果非光性相移取决于起搏器的相位，则两个PRC应为同相。我们用欧洲黄鼠(Spermophilus Citellus)进行了非光学夹带实验，以区分这两种可能性。10只欧洲黄鼠被饲养在暗淡的红光(1lux)和20±1°C下，在实验的夹带阶段，动物每23.5 h(T)被限制在一个跑轮上3h，其中6只松鼠有昼夜节律，2只继续自由奔跑，2只可能被夹带但表现出心律失常。在第二个实验中，在类似的方案中使用了光脉冲。9只松鼠中有5只被缠绕，1只没有被缠绕，3只结果不明确。在稳定夹带期间，相位推进的非光脉冲与主观一天的结束一致，而相位推进的光脉冲与主观一天的开始一致：平均[.PSI]无光=11.4h；平均[.PSI]光=0.9h([.PSI]定义为活动开始和脉冲开始之间的差值)。非光性夹带的数据与在夜间活动的叙利亚仓鼠的类似实验中得到的数据很好地吻合，其中[.PSI]无光性变化从8.09到11.34h，这表明对非光性活动诱导刺激的昼夜相响应取决于起搏器的相而不是活动周期的相。
Entrainment by nonphotic, activity-inducing stimuli has been investigated in detail in nocturnal rodents, but little is known about nonphotic entrainment in diurnal animals. Comparative studies would offer the opportunity to distinguish between two possibilities. (1) If nonphotic phase shifts depend on the phase of the activity cycle, the phase response curve (PRC) should be about 180° out of phase in nocturnal and diurnal mammals. (2) If nonphotic phase shifts depend on the phase of the pacemaker, the two PRCs should be in phase. We used the diurnalEuropean ground squirrel (Spermophilus citellus) in a nonphotic entrainment experiment to distinguish between the two possibilities. Ten European ground squirrels were kept under dim red light (<1 lux) and 20 ± 1° C. During the entrainment phase of the experiment, the animals were confined every 23.5 h (T) to a running wheel for 3 h. The circadian rhythms of 6 squirrels entrained, 2 continued to free run, and 2 possibly entrained but displayed arrhythmicity during the experiment. In a second experiment, a photic pulse was used in a similar protocol. Five out of 9 squirrels entrained, 1 did not entrain, and 3 yielded ambiguous results. During stable entrainment, the phase-advancing nonphotic pulses coincided with the end of the subjective day, while phase-advancing light pulses coincided with the start of the subjective day: mean [.psi]nonphotic = 11.4 h; mean [.psi]photic =0.9h([.psi] defined as the difference between the onset of activity and the start of the pulse). The data for nonphotic entrainment correspond well with those from similar experiments with nocturnal Syrian hamsters where [.psi]nonphotic varied from 8.09 to 11.34 h. This indicates that the circadian phase response to a nonphotic activity-inducing stimulus depends on the phase of the pacemaker rather than on the phase of the activity cycle.
人类昼夜节律起搏器的非光夹带。
DOI：
10.1152/ajpregu.1998.274.4.r991
发表时间：
1998
期刊：
The American journal of physiology
影响因子：
--
作者：
Klerman,EB;Rimmer,DW;Dijk,DJ;Kronauer,RE;Rizzo3rd,JF;Czeisler,CA
通讯作者：
Czeisler,CA
影响因子：
--
作者：
EDGAR, DM;DEMENT, WC
通讯作者：
DEMENT, WC