Geographic and Individual Associations with PrEP Stigma: Results from the RADAR Cohort of Diverse Young Men Who have Sex with Men and Transgender Women.

Geographic and Individual Associations with PrEP Stigma: Results from the RADAR Cohort of Diverse Young Men Who have Sex with Men and Transgender Women.
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DOI:
10.1007/s10461-018-2159-5
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发表时间:
2018-09
期刊:
影响因子:
4.4
通讯作者:
Smith JD
Smith JD
中科院分区:
医学2区
文献类型:
--
作者:
Mustanski B;Ryan DT;Hayford C;Phillips G 2nd;Newcomb ME;Smith JD

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增加接触前预防(PrEP)的使用,以防止高危人群(如男青年)感染艾滋病毒,对减缓艾滋病毒流行至关重要。污名化和消极的强制性规范,如所谓的“Truvada妓女”现象,阻碍了这一努力。我们研究了YMSM和跨性别妇女以及相关的个人和地理空间因素之间的PrEP耻辱和强制性规范信念的患病率和类型。在一项正在进行的纵向队列研究中,620名参与者接受了一项新创建的PrEP污名和积极态度措施。结果表明,与黑人和拉丁裔参与者相比,白色参与者的耻辱感较低,并且参与者不认为自己是男性。事先了解PrEP与较低的耻辱感和较高的积极态度有关。PrEP污名具有显著的地理空间聚集性,在艾滋病毒发病率高和少数民族集中的社区确定了热点,而在艾滋病毒发病率高和LGBT污名低的地区确定了冷点。这些结果提供了有关PrEP态度以及PrEP污名如何在个人和社区之间存在差异的重要信息。
Increasing the uptake of pre-exposure prophylaxis (PrEP) to prevent HIV acquisition among at-risk populations, such as young men who have sex with men (YMSM), is of vital importance to slowing the HIV epidemic. Stigma and negative injunctive norms, such as the so called “Truvada Whore” phenomenon, hamper this effort. We examined the prevalence and types of PrEP stigma and injunctive norm beliefs among YMSM and transgender women and associated individual and geospatial factors. A newly created measure of PrEP Stigma and Positive Attitudes was administered to 620 participants in an ongoing longitudinal cohort study. Results indicated lower stigma among White, compared to Black and Latino participants, and among participants not identifying as male. Prior knowledge about PrEP was associated with lower stigma and higher positive attitudes. PrEP stigma had significant geospatial clustering and hotspots were identified in neighborhoods with high HIV incidence and concentration of racial minorities, whereas coldspots were identified in areas with high HIV incidence and low LGBT stigma. These results provide important information about PrEP attitudes and how PrEP stigma differs between individuals and across communities.
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