Stigma and Conspiracy Beliefs Related to Pre-exposure Prophylaxis (PrEP) and Interest in Using PrEP Among Black and White Men and Transgender Women Who Have Sex with Men.

Stigma and Conspiracy Beliefs Related to Pre-exposure Prophylaxis (PrEP) and Interest in Using PrEP Among Black and White Men and Transgender Women Who Have Sex with Men.
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DOI:
10.1007/s10461-017-1690-0
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发表时间:
2017-05
期刊:
影响因子:
4.4
通讯作者:
Maksut J
Maksut J
中科院分区:
医学2区
文献类型:
--
作者:
Eaton LA;Kalichman SC;Price D;Finneran S;Allen A;Maksut J

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艾滋病毒/艾滋病在美国的流行持续存在,特别是在种族、性取向和性别少数人群中。暴露前预防(PrEP),或使用抗逆转录病毒药物预防艾滋病毒,是一种有效的选择,但PrEP的吸收一直很慢。使用PrEP的社会文化障碍在很大程度上没有得到充分重视,但有可能阻碍吸收,因此需要进一步了解。为了评估PrEP的潜在障碍之间的关系(即,PrEP耻辱和阴谋信念),以及对PrEP的兴趣,与男性发生性关系的黑人男性和变性女性(BMTW,N = 85)和白色MTW(WMTW,N = 179)在2015年美国东南部一个大城市的同性恋骄傲活动中进行了调查。完成了双变量和多变量logistic回归分析,以检查与PrEP兴趣相关的因素。在整个样本中,观察到中等水平的PrEP意识(63%)和低水平的使用(9%)。相信PrEP是为滥交的人(耻辱信念)与缺乏使用PrEP的兴趣密切相关,并且赞同这种信念的人更有可能报告性冒险行为。与PrEP相关的阴谋信念在样本的大部分少数人(42%)中报告,并且在BMTW中比WMTW更频繁地报告。鉴于大力强调使用生物医学战略预防艾滋病毒,迫切需要解决获得PrEP的社会文化障碍,如果不这样做,将削弱生物医学预防的潜在好处。
The HIV/AIDS epidemic in the US continues to persist, in particular, among race, sexual orientation, and gender minority populations. Pre-exposure prophylaxis (PrEP), or using antiretroviral medications for HIV prevention, is an effective option, but uptake of PrEP has been slow. Sociocultural barriers to using PrEP have been largely underemphasized, yet have the potential to stall uptake and, therefore, warrant further understanding. In order to assess the relationships between potential barriers to PrEP (i.e., PrEP stigma and conspiracy beliefs), and interest in PrEP, Black men and transgender women who have sex with men (BMTW, N = 85) and White MTW (WMTW, N = 179) were surveyed at a gay pride event in 2015 in a large southeastern US city. Bivariate and multivariate logistic regression analyses were completed to examine factors associated with PrEP interest. Among the full sample, moderate levels of PrEP awareness (63%) and low levels of use (9%) were observed. Believing that PrEP is for people who are promiscuous (stigma belief) was strongly associated with lack of interest in using PrEP, and individuals who endorsed this belief were more likely to report sexual risk taking behavior. Conspiracy beliefs related to PrEP were reported among a large minority of the sample (42%) and were more frequently reported among BMTW than WMTW. Given the strong emphasis on the use of biomedical strategies for HIV prevention, addressing sociocultural barriers to PrEP access is urgently needed and failure to do so will weaken the potential benefits of biomedical prevention.
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