A framework for the study of zoonotic disease emergence and its drivers: spillover of bat pathogens as a case study.
A framework for the study of zoonotic disease emergence and its drivers: spillover of bat pathogens as a case study.
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DOI：
10.1098/rstb.2012.0228
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发表时间：
2012-10-19
期刊：
影响因子：
--
通讯作者：
Cunningham AA
中科院分区：
文献类型：
--
作者：
Wood JL;Leach M;Waldman L;Macgregor H;Fooks AR;Jones KE;Restif O;Dechmann D;Hayman DT;Baker KS;Peel AJ;Kamins AO;Fahr J;Ntiamoa-Baidu Y;Suu-Ire R;Breiman RF;Epstein JH;Field HE;Cunningham AA
许多严重的新发人畜共患传染病最近都是由蝙蝠引起的，包括埃博拉病毒、马尔堡病毒、SARS冠状病毒、亨德拉病毒、尼帕病毒以及一些狂犬病和狂犬病相关病毒，这与野生动物是人类新发人畜共患传染病的重要来源这一总体观察结果一致。人们对生态系统健康与人类健康之间公认的联系的基本机制仍然知之甚少，对助长疾病出现和传播的生态、社会和经济条件作出适当反应是一项重大的社会挑战。在野生动物出现疾病的情况下，应保护野生动物和生境，这反过来将保护重要的生态系统结构和功能，这对人类福祉和环境可持续性具有更广泛的影响，同时尽量减少野生动物病原体对人类的溢出。在这篇综述中，我们提出了一个新的框架，整体和跨学科的人畜共患病的出现及其驱动因素的调查，蝙蝠病原体的溢出作为一个案例研究。这项研究的目的是获得详细的跨学科理解，它结合了自然科学和社会科学的前沿观点，与公共卫生，土地利用和保护的政策影响有关。
Many serious emerging zoonotic infections have recently arisen from bats, including Ebola, Marburg, SARS-coronavirus, Hendra, Nipah, and a number of rabies and rabies-related viruses, consistent with the overall observation that wildlife are an important source of emerging zoonoses for the human population. Mechanisms underlying the recognized association between ecosystem health and human health remain poorly understood and responding appropriately to the ecological, social and economic conditions that facilitate disease emergence and transmission represents a substantial societal challenge. In the context of disease emergence from wildlife, wildlife and habitat should be conserved, which in turn will preserve vital ecosystem structure and function, which has broader implications for human wellbeing and environmental sustainability, while simultaneously minimizing the spillover of pathogens from wild animals into human beings. In this review, we propose a novel framework for the holistic and interdisciplinary investigation of zoonotic disease emergence and its drivers, using the spillover of bat pathogens as a case study. This study has been developed to gain a detailed interdisciplinary understanding, and it combines cutting-edge perspectives from both natural and social sciences, linked to policy impacts on public health, land use and conservation.
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影响因子：
2.5
作者：
Breed AC;Field HE;Smith CS;Edmonston J;Meers J
通讯作者：
Meers J
DOI：
10.1073/pnas.1006219107
发表时间：
2010-12-14
影响因子：
11.1
作者：
Chan, Emily H.;Brewer, Timothy F.;Brownstein, John S.
通讯作者：
Brownstein, John S.
影响因子：
5.4
作者：
Bloom, Gerald;Standing, Hilary;Lloyd, Robert
通讯作者：
Lloyd, Robert
DOI：
10.2307/3504095
发表时间：
1988-01-01
期刊：
Mammalian Species
影响因子：
--
作者：
DEFREES S L;WILSON D E
通讯作者：
WILSON D E
影响因子：
2.7
作者：
Daszak, P;Cunningham, AA;Hyatt, AD
通讯作者：
Hyatt, AD