Cep55: abscission boss or assistant?
Cep55: abscission boss or assistant?
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DOI:
10.1016/j.tcb.2021.07.006
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发表时间:
2021-10
影响因子:
19
通讯作者:
Dwyer, Noelle D.
中科院分区:
文献类型:
--
作者:
Little, Jessica N.;Dwyer, Noelle D.
Abscission is the second stage of cytokinesis. Cep55, a coiled-coil protein, is thought to recruit ESCRTs to the midbody to complete abscission. However, recent studies of Cep55 knockout mice reveal that most cells can complete abscission without Cep55. More work is needed to understand abscission mechanisms in different cell types.
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