Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis.

Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis.
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DOI:
10.1177/14799731211002240
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发表时间:
2021-01
影响因子:
4.1
通讯作者:
Vilaró J
Vilaró J
中科院分区:
医学3区
文献类型:
--
作者:
Cares-Marambio K;Montenegro-Jiménez Y;Torres-Castro R;Vera-Uribe R;Torralba Y;Alsina-Restoy X;Vasconcello-Castillo L;Vilaró J

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由于2019冠状病毒病(COVID-19)发病时间相对较晚,因此对该疾病后遗症的了解仍然有限。然而,关于COVID-19之前其他类型冠状病毒感染的文献报告称,患者在出院后可能会出现持续症状。确定COVID-19感染后住院幸存者的呼吸道症状患病率。对五个数据库进行了一项活体系统性综述,以确定报告COVID-19患者出院后呼吸道症状持续存在的研究。两名独立研究人员审查和分析了现有文献,然后提取和评估这些文章的质量。在初始检索返回的1,154份报告中,发现了9篇文章,其中1,816例患者被纳入数据合成。在汇总分析中,我们发现患病率为0.52(CI 0.38-0.66,p < 0.01,I2 = 97%),0.37疲劳、呼吸困难、胸痛和咳嗽的CI分别为0.28-0.48,p < 0.01,I2 = 93%)、0.16(CI 0.10-0.23,p < 0.01,I2 = 90%)和0.14(CI 0.06-0.24,p < 0.01,I2 = 96%)。疲劳、呼吸困难、胸痛和咳嗽是最常见的呼吸道症状,在COVID-19住院幸存者出院后3周至3个月内分别有52%、37%、16%和14%的患者出现。
Knowledge on the sequelae of Coronavirus Disease 2019 (COVID-19) remains limited due to the relatively recent onset of this pathology. However, the literature on other types of coronavirus infections prior to COVID-19 reports that patients may experience persistent symptoms after discharge. To determine the prevalence of respiratory symptoms in survivors of hospital admission after COVID-19 infection. A living systematic review of five databases was performed in order to identify studies which reported the persistence of respiratory symptoms in COVID-19 patients after discharge. Two independent researchers reviewed and analysed the available literature, and then extracted and assessed the quality of those articles. Of the 1,154 reports returned by the initial search nine articles were found, in which 1,816 patients were included in the data synthesis. In the pooled analysis, we found a prevalence of 0.52 (CI 0.38–0.66, p < 0.01, I 2 = 97%), 0.37 (CI 0.28–0.48, p < 0.01, I 2 = 93%), 0.16 (CI 0.10–0.23, p < 0.01, I 2 = 90%) and 0.14 (CI 0.06–0.24, p < 0.01, I 2 = 96%) for fatigue, dyspnoea, chest pain, and cough, respectively. Fatigue, dyspnoea, chest pain, and cough were the most prevalent respiratory symptoms found in 52%, 37%, 16% and 14% of patients between 3 weeks and 3 months, after discharge in survivors of hospital admission by COVID-19, respectively.
DOI: 10.36141/svdld.v37i2.9234
发表时间: 2020
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影响因子: --
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