Molecular epidemiological studies of human herpesvirus 6 in families

Molecular epidemiological studies of human herpesvirus 6 in families
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人类疱疹病毒6型家庭分子流行病学研究

DOI:
10.1002/jmv.1890420303
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发表时间:
1994
影响因子:
12.7
通讯作者:
K. Yamanishi
K. Yamanishi
中科院分区:
医学3区
文献类型:
--
作者:
T. Mukai;Takeshi Yamamoto;T. Kondo;K. Kondo;T. Okuno;H. Kosuge;K. Yamanishi

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应用分子流行病学技术对4个家庭的人类疱疹病毒6型(HHV-6)的传播方式进行了调查。HHV-6是从7名患有皮疹的婴儿(包括兄弟姐妹)的外周血和2名母亲的唾液中分离出来的。这些菌株进行了检查,通过限制性内切酶分析纯化的DNA的遗传相关性。虽然家庭之间的消化模式的配置文件不同,他们是非常相似的,在一个特定的家庭。这些结果可能表明,HHV-6主要由母亲传播给孩子。© 1994 Wiley利斯公司
The mode of transmission of human herpesvirus 6 (HHV‐6) was investigated by molecular epidemiological techniques in four families. HHV‐6 was isolated from the peripheral blood of seven infants with exanthem subitum, including siblings, and from the saliva of two mothers. These isolates were examined for genetic relatedness by means of restriction enzymes analysis of purified DNA. While the profiles of the digestion patterns differed among families, they were very similar in a particular family. These results may suggest that HHV‐6 is transmitted primarily from mother to child. © 1994 Wiley‐Liss, Inc.
来自北美婴儿的人类疱疹病毒 6 分离株的表型和遗传多态性。
DOI: 10.1016/0042-6822(92)91240-u
发表时间: 1992
期刊: Virology
影响因子: 3.7
作者:
Dewhurst,S;Chandran,B;McIntyre,K;Schnabel,K;Hall,CB
通讯作者: Hall,CB
DOI: 10.1016/0042-6822(91)90424-a
发表时间: 1991-10-01
期刊: VIROLOGY
影响因子: 3.7
作者:
ABLASHI, DV;BALACHANDRAN, N;GALLO, RC
通讯作者: GALLO, RC