Hypersomnia and depressive symptoms: methodological and clinical aspects.
Hypersomnia and depressive symptoms: methodological and clinical aspects.
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DOI：
10.1186/1741-7015-11-78
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发表时间：
2013-03-21
期刊：
影响因子：
9.3
通讯作者：
Bayard S
中科院分区：
文献类型：
--
作者：
Dauvilliers Y;Lopez R;Ohayon M;Bayard S
抑郁症状和睡眠过度之间的关联是复杂的，通常是双向的。在一般人群中，与过度嗜睡相关的许多疾病中，最常见的是精神健康疾病，特别是抑郁症。然而，大多数针对嗜睡症的情绪障碍研究都使用单一反应来评估日间嗜睡，忽略了有关症状严重程度，持续时间和夜间睡眠质量的关键和临床相关信息。只有少数研究使用客观的工具，如多导睡眠图，直接测量白天和夜间睡眠倾向的抑郁症与正常的平均睡眠潜伏期和睡眠时间。情绪障碍中的嗜睡症，而不是一种医疗条件本身，更是一种主观的睡眠投诉，而不是一个客观的发现。情绪症状也经常被报告在中枢起源的睡眠过度障碍，特别是在嗜睡症。下丘脑分泌素缺乏可能是这种情况的一个促成因素。需要进一步的干预性研究来探讨是否管理的睡眠投诉改善情绪症状的睡眠过度障碍，相反，是否管理的情绪投诉改善睡眠症状的情绪障碍。
The associations between depressive symptoms and hypersomnia are complex and often bidirectional. Of the many disorders associated with excessive sleepiness in the general population, the most frequent are mental health disorders, particularly depression. However, most mood disorder studies addressing hypersomnia have assessed daytime sleepiness using a single response, neglecting critical and clinically relevant information about symptom severity, duration and nighttime sleep quality. Only a few studies have used objective tools such as polysomnography to directly measure both daytime and nighttime sleep propensity in depression with normal mean sleep latency and sleep duration. Hypersomnia in mood disorders, rather than a medical condition per se, is more a subjective sleep complaint than an objective finding. Mood symptoms have also been frequently reported in hypersomnia disorders of central origin, especially in narcolepsy. Hypocretin deficiency could be a contributing factor in this condition. Further interventional studies are needed to explore whether management of sleep complaints improves mood symptoms in hypersomnia disorders and, conversely, whether management of mood complaints improves sleep symptoms in mood disorders.
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