Association of sedentary behaviour with metabolic syndrome: a meta-analysis.
Association of sedentary behaviour with metabolic syndrome: a meta-analysis.
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DOI：
10.1371/journal.pone.0034916
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Biddle SJ
中科院分区：
文献类型：
--
作者：
Edwardson CL;Gorely T;Davies MJ;Gray LJ;Khunti K;Wilmot EG;Yates T;Biddle SJ
近年来，人们对久坐行为（坐姿）与健康结果之间的关系越来越感兴趣。直到最近才有研究评估久坐行为与代谢综合征之间的关联。本研究的目的是量化久坐行为和代谢综合征之间的关联，在成年人使用荟萃分析。使用与久坐行为和代谢综合征相关的医学主题词和关键词检索Medline、Embase和科克伦图书馆。手动检索相关文章和个人数据库的参考文献列表。入选标准为：（1）横断面或前瞻性设计;（2）包括≥18岁的成人;（3）自我报告或客观测量的久坐时间;（4）代谢综合征的结局指标。每项研究提取了代谢综合征的比值比（OR）和95%置信区间，将久坐行为的最高水平与最低水平进行比较。使用随机效应模型合并数据，以考虑研究之间的异质性。确定了10项横断面研究（n =21393名参与者），1项高质量研究，4项中等质量研究和5项低质量研究。 久坐的时间越长，代谢综合征的几率增加73%（OR 1.73，95%CI 1.55-1.94，p<0.0001）。性别、久坐行为指标、代谢综合征定义、研究质量或国家收入亚组之间无差异。没有证据表明存在统计异质性（I2 = 0.0%，p = 0.61）或发表偏倚（Eggers检验t = 1.05，p = 0.32）。 久坐不动的人患代谢综合征的几率更大。减少久坐行为对预防代谢综合征可能很重要。
In recent years there has been a growing interest in the relationship between sedentary behaviour (sitting) and health outcomes. Only recently have there been studies assessing the association between time spent in sedentary behaviour and the metabolic syndrome. The aim of this study is to quantify the association between sedentary behaviour and the metabolic syndrome in adults using meta-analysis. Medline, Embase and the Cochrane Library were searched using medical subject headings and key words related to sedentary behaviours and the metabolic syndrome. Reference lists of relevant articles and personal databases were hand searched. Inclusion criteria were: (1) cross sectional or prospective design; (2) include adults ≥18 years of age; (3) self-reported or objectively measured sedentary time; and (4) an outcome measure of metabolic syndrome. Odds Ratio (OR) and 95% confidence intervals for metabolic syndrome comparing the highest level of sedentary behaviour to the lowest were extracted for each study. Data were pooled using random effects models to take into account heterogeneity between studies. Ten cross-sectional studies (n = 21393 participants), one high, four moderate and five poor quality, were identified. Greater time spent sedentary increased the odds of metabolic syndrome by 73% (OR 1.73, 95% CI 1.55–1.94, p<0.0001). There were no differences for subgroups of sex, sedentary behaviour measure, metabolic syndrome definition, study quality or country income. There was no evidence of statistical heterogeneity (I2 = 0.0%, p = 0.61) or publication bias (Eggers test t = 1.05, p = 0.32). People who spend higher amounts of time in sedentary behaviours have greater odds of having metabolic syndrome. Reducing sedentary behaviours is potentially important for the prevention of metabolic syndrome.
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影响因子：
16.2
作者：
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通讯作者：
Ford, ES
影响因子：
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作者：
Matthews, Charles E.;Chen, Kong Y.;Troiano, Richard P.
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作者：
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DOI：
10.1161/atvbaha.107.151092
发表时间：
2008-04-01
影响因子：
8.7
作者：
Grundy, Scott M.
通讯作者：
Grundy, Scott M.