Annonaceae: Breaking the Wall of Inflammation.

Annonaceae: Breaking the Wall of Inflammation.
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DOI:
10.3389/fphar.2017.00752
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发表时间:
2017
影响因子:
5.6
通讯作者:
Husain K
Husain K
中科院分区:
医学2区
文献类型:
--
作者:
Attiq A;Jalil J;Husain K

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热带森林的目录已将番荔枝科列为最多样化的植物科之一。几个世纪以来,它被用于传统药物治疗各种病理条件,包括蛇咬伤,止痛,收敛,腹泻,痢疾,关节炎疼痛,风湿病,神经痛和体重减轻等。番荔枝科的植物化学分析报告了生物碱,黄酮,三萜,二萜和二萜黄酮苷,甾醇,木脂素,和番荔枝内酯特征性地隶属于番荔枝科物种。许多过去的研究已经强调了番荔枝科物种的粗提取物和分离的化合物的多效药理活性。本文对番荔枝科植物的民族植物学、形态学、植物化学、毒性以及抗炎活性等方面的研究进行了综述。
Inventories of tropical forests have listed Annonaceae as one of the most diverse plant families. For centuries, it is employed in traditional medicines to cure various pathological conditions including snakebite, analgesic, astringent, diarrhea, dysentery, arthritis pain, rheumatism, neuralgia, and weight loss etc. Phytochemical analysis of Annonaceae family have reported the occurrence of alkaloids, flavonoids, triterpenes, diterpenes and diterpene flavone glycosides, sterols, lignans, and annonaceous acetogenin characteristically affiliated with Annonaceae sp. Numerous past studies have underlined the pleotropic pharmacological activities of the crude extracts and isolated compounds from Annonaceae species. This review is an effort to abridge the ethnobotany, morphology, phytochemistry, toxicity, and particularly focusing on the anti-inflammatory activity of the Annonaceae species.
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