Social affiliation relates to tyrosine hydroxylase immunolabeling in male and female zebra finches (Taeniopygia guttata).
Social affiliation relates to tyrosine hydroxylase immunolabeling in male and female zebra finches (Taeniopygia guttata).
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DOI：
10.1016/j.jchemneu.2011.05.005
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发表时间：
2011-09
影响因子：
2.8
通讯作者：
Riters LV
中科院分区：
文献类型：
--
作者：
Alger SJ;Juang C;Riters LV
儿茶酚胺类物质多巴胺和去甲肾上腺素与亲和行为有关，但很少有研究涉及不同社会环境中的亲和行为在多大程度上依赖于相似或不同的儿茶酚胺能机制。为了探讨儿茶酚胺在不同的长期社会背景下的亲和行为的作用，我们研究了密度的儿茶酚胺合成酶酪氨酸羟化酶（TH）在中脑边缘多巴胺能系统和“社会行为网络”的男性和女性斑马雀（Taeniopygia guttata）配对21天，无论是相同的或相反的性别同种的大脑区域。在配对后的第16-21天，同性和异性配对的成员产生了相似的亲和行为。与腹侧被盖区（VTA）、伏隔核（AC）、内侧视前核（POM）和下丘脑腹内侧核（VMH）中TH标记相关的联系测量。TH标记密度和具体措施的附属行为之间的关系不同，在吻侧相比，尾侧的AC和VTA的亚区，这表明这些亚区在附属行为的调节不同的作用。最后，TH标记密度的VMH和吻侧腹侧被盖区正相关的求爱量收到的合作伙伴和TH标记在AC是密集的异性对相比，同性对，表明社会诱导的大脑可塑性。总体而言，结果突出了一个复杂的区域和行为的特定作用，在脊椎动物的联系，儿茶酚胺。
The catecholamines dopamine and norepinephrine are implicated in affiliative behaviors, yet few studies have addressed the extent to which affiliative behaviors within distinct social settings rely upon similar or distinct catecholaminergic mechanisms. To explore the role of catecholamines in affiliative behavior within distinct long-term social contexts, we examined the density of the catecholamine synthetic enzyme tyrosine hydroxylase (TH) in brain regions within both the mesolimbic dopaminergic system and “social behavior network” in male and female zebra finches (Taeniopygia guttata) paired for 21 days with either a same- or opposite-sex conspecific. On days 16-21 after pairing, members of both same- and mixed-sex pairs produced similar rates of affiliative behaviors. Measures of affiliation related to TH labeling in the ventral tegmental area (VTA), nucleus accumbens (Ac), medial preoptic nucleus (POM), and ventromedial nucleus of the hypothalamus (VMH). Relationships between TH labeling density and specific measures of affiliative behavior differed in rostral compared to caudal subregions of Ac and VTA, suggesting distinct roles for these subregions in the regulation of affiliative behavior. Finally, TH labeling density in the VMH and rostral VTA were positively related to the amount of courtship received from the partner and TH labeling in Ac was denser in opposite-sex pairs compared to same-sex pairs, indicative of socially-induced brain plasticity. Overall, results highlight a complex region- and behavior-specific role for catecholamines in vertebrate affiliation.
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影响因子：
1.3
作者：
Dunn, AM;Zann, RA
通讯作者：
Zann, RA
影响因子：
3.2
作者：
Etgen, AM;Morales, JC
通讯作者：
Morales, JC
影响因子：
1.9
作者：
Gingrich, B;Liu, Y;Insel, TR
通讯作者：
Insel, TR
影响因子：
3.2
作者：
Cavanaugh BL;Lonstein JS
通讯作者：
Lonstein JS
影响因子：
2.5
作者：
BAILHACHE, T;BALTHAZART, J
通讯作者：
BALTHAZART, J