SERS-based plasmonic nanobiosensing in single living cells.
SERS-based plasmonic nanobiosensing in single living cells.
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DOI:
10.1007/s00216-008-2521-y
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发表时间:
2009-02
影响因子:
4.3
通讯作者:
Vo-Dinh, Tuan
中科院分区:
文献类型:
--
作者:
Scaffidi, Jonathan P.;Gregas, Molly K.;Seewaldt, Victoria;Vo-Dinh, Tuan
In this paper, we describe the development and application of a pH-sensitive plasmonics-active fiber-optic nanoprobe suitable for intracellular bioanalysis in single living human cells using surface-enhanced Raman scattering (SERS) detection. The effectiveness and usefulness of SERS-based fiber-optic nanoprobes are illustrated by measurements of intracellular pH in HMEC-15/hTERT immortalized “normal” human mammary epithelial cells and PC-3 human prostate cancer cells. The results indicate that fiber-optic nanoprobe insertion and interrogation provide a sensitive and selective means to monitor cellular microenvironments at the single cell level.
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影响因子:
15
作者:
Cao, YC;Jin, RC;Mirkin, CA
通讯作者:
Mirkin, CA
DOI:
10.1073/pnas.2232479100
发表时间:
2003-11-11
影响因子:
11.1
作者:
Hirsch, LR;Stafford, RJ;West, JL
通讯作者:
West, JL
影响因子:
7.4
作者:
Isola, NR;Stokes, DL;Vo-Dinh, T
通讯作者:
Vo-Dinh, T
影响因子:
7.4
作者:
Culha, M;Stokes, D;Vo-Dinh, T
通讯作者:
Vo-Dinh, T
影响因子:
4.5
作者:
JEANMAIRE, DL;VANDUYNE, RP
通讯作者:
VANDUYNE, RP