Discrepancy between Self-Reported and Urine Cotinine-Verified Environmental Tobacco Smoke Exposure among Rural Pregnant Women in China.

Discrepancy between Self-Reported and Urine Cotinine-Verified Environmental Tobacco Smoke Exposure among Rural Pregnant Women in China.
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中国农村孕妇自我报告与尿液可替宁验证环境烟草烟雾暴露之间的差异

DOI:
10.3390/ijerph15071499
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发表时间:
2018-07-16
影响因子:
--
通讯作者:
Seto E
Seto E
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Xiao X;Li Y;Song X;Xu Q;Yang S;Wu J;Seto E

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产前暴露于环境烟草烟雾(ETS)是与不良儿童健康结果相关的最易改变的风险因素。然而,很少有纵向研究,以比较自报(SR)和尿可替宁(UC)验证的ETS暴露之间的差异率在妊娠三个月,特别是在农村地区。本研究的目的是评估农村妇女在整个怀孕期间采用三种措施进行SR和UC验证的ETS暴露之间的差异,并探索与这些差异相关的预测因素。本研究使用了一个前瞻性产前队列,包括420名孕妇,其ETS暴露在整个三个孕期的SR和UC验证进行了全面评估。通过SR验证评估环境烟草暴露,并使用UC的检测限进行验证。每三个月的差异率进行了测定。多变量逻辑回归用于评估与这些差异相关的预测因素。SR和UC验证之间的差异率分别为25.2%,17.1%和20.5%(第一,第二和第三季度)。最高的不一致性发生在前三个月。调整混杂因素后,发现以下变量与SR和UC验证的ETS暴露之间的差异率具有统计学显著性相关性:家庭中吸烟者的数量和家庭收入的所有三个月,乡镇网站的中期和晚期妊娠,妊娠的最后三个月。农村孕妇ETS暴露的SR率低报,而UC核实的暴露率较高。家庭中吸烟者较多和怀孕可能会增加孕妇接触ETS的风险。在整个怀孕期间进行生物化学验证是必要的,以通过家庭吸烟禁令和促进社区无烟计划。
Prenatal exposure to environmental tobacco smoke (ETS) is the most modifiable risk factor associated with adverse child-health outcomes. However, few longitudinal studies are implemented to compare the rates of discrepancy between self-reported (SR) and urinary cotinine (UC)-verified ETS exposure during the three trimesters of pregnancy, especially in rural areas. The objectives of this study were to assess the discrepancy between SR and UC-verified ETS exposure among rural women employing three measures throughout pregnancy, and to explore predictors related to these differences. This study used a prospective prenatal cohort consisting of 420 pregnant women whose ETS exposure was entirely evaluated by both SR and UC verification across three trimesters of pregnancy. Environmental tobacco exposure was assessed via SR verification, and was validated using the limit of detection for UC. The discrepancy rates were determined for each trimester. Multivariate logistic regression was used to assess the predictors associated with these differences. The discrepancy rates between SR and UC verification were 25.2%, 17.1%, and 20.5% (first, second, and third trimester, respectively). The highest inconsistency occurred in the first trimester. After adjusting for confounding factors, the following variables were found to have statistically significant associations with the discrepancy rate between SR and UC-verified ETS exposure: the number of smokers in the family and household income for all three trimesters, township site for the second and third trimester, and gravidity for the last trimester. The SR rate of ETS exposure among rural pregnant women is underreported, while the UC-verified rate is higher. More smokers in the family and gravidity may increase the risk of ETS exposure for pregnant women. Biochemical validation is warranted throughout pregnancy for the adoption of home-smoking bans and the promotion of community-based smoke-free programs.
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