The impact of ventilation rate on reducing the microorganisms load in the air and on surfaces in a room-sized chamber.
The impact of ventilation rate on reducing the microorganisms load in the air and on surfaces in a room-sized chamber.
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DOI：
10.1111/ina.13161
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发表时间：
2022-11
期刊：
影响因子：
5.8
通讯作者：
Noakes, Catherine J.
中科院分区：
文献类型：
--
作者：
Hiwar, Waseem;King, Marco-Felipe;Kharrufa, Harith;Tidswell, Emma;Fletcher, Louise A.;Noakes, Catherine J.
关键词：
医院获得性感染（HAI）是一项全球性挑战，导致死亡率和高昂的治疗成本。由于空气和表面污染，环境在传播中起着重要作用。这包括微生物从空气中沉积到表面上。量化微生物的沉积速率可以了解表面污染，并可以为减轻感染风险的策略提供信息。我们开发并验证了一种新的自动多板被动空气采样（AMPAS）设备。这使得能够在受控的时间段内收集被动沉积样品的序列，而无需人为干预。AMPAS与空气采样一起使用，以测量通风率和空间位置对32 m3室内气溶胶化金黄色葡萄球菌沉积速率的影响。将通风率从3个ACH增加到6个ACH，导致空气和表面上的微生物负荷分别减少45% ± 10%和44% ± 32%。内表面上的沉积速率λd计算为1.38 ± 0.48 h−1。空气中和表面微生物的样本采取更接近通风供应显示出较低的浓度比接近提取物。研究结果支持了控制通风和环境参数以减轻医院环境中空气和表面感染风险的重要性。
Hospital‐acquired infections (HAIs) are a global challenge incurring mortalities and high treatment costs. The environment plays an important role in transmission due to contaminated air and surfaces. This includes microorganisms' deposition from the air onto surfaces. Quantifying the deposition rate of microorganisms enables understanding surface contamination and can inform strategies to mitigate the infection risk. We developed and validated a novel Automated Multiplate Passive Air Sampling (AMPAS) device. This enables sequences of passive deposition samples to be collected over a controlled time period without human intervention. AMPAS was used with air sampling to measure the effect of ventilation rate and spatial location on the deposition rate of aerosolized Staphylococcus aureus in a 32 m3 chamber. Increasing the ventilation rate from 3 to 6 ACH results in a reduction of microbial load in the air and on surfaces by 45% ± 10% and 44% ± 32%, respectively. The deposition rate onto internal surfaces λd was calculated as 1.38 ± 0.48 h−1. Samples of airborne and surface microorganisms taken closer to the ventilation supply showed a lower concentration than close to the extract. The findings support the importance of controlling the ventilation and the environmental parameters to mitigate both air and surface infection risks in the hospital environment.
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