Emerging functions for the Staphylococcus aureus RNome.
Emerging functions for the Staphylococcus aureus RNome.
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DOI:
10.1371/journal.ppat.1003767
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发表时间:
2013
期刊:
影响因子:
6.7
通讯作者:
Felden B
中科院分区:
文献类型:
--
作者:
Guillet J;Hallier M;Felden B
Staphylococcus aureus is a leading pathogen for animals and humans, not only being one of the most frequently isolated bacteria in hospital-associated infections but also causing diseases in the community. To coordinate the expression of its numerous virulence genes for growth and survival, S. aureus uses various signalling pathways that include two-component regulatory systems, transcription factors, and also around 250 regulatory RNAs. Biological roles have only been determined for a handful of these sRNAs, including cis, trans, and cis-trans acting RNAs, some internally encoding small, functional peptides and others possessing dual or multiple functions. Here we put forward an inventory of these fascinating sRNAs; the proteins involved in their activities; and those involved in stress response, metabolisms, and virulence.
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影响因子:
3.7
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影响因子:
14.9
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4.4
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3.2
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通讯作者:
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