Thirdhand Smoke: New Evidence, Challenges, and Future Directions.

Thirdhand Smoke: New Evidence, Challenges, and Future Directions.
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DOI:
10.1021/acs.chemrestox.6b00343
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发表时间:
2017-01-17
影响因子:
4.1
通讯作者:
Whitehead TP
Whitehead TP
中科院分区:
医学3区
文献类型:
--
作者:
Jacob P 3rd;Benowitz NL;Destaillats H;Gundel L;Hang B;Martins-Green M;Matt GE;Quintana PJ;Samet JM;Schick SF;Talbot P;Aquilina NJ;Hovell MF;Mao JH;Whitehead TP

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三手烟(Thirdhand Smoke,简称THS)是指二手烟草烟雾排放到空气中后持续存在的污染。它指的是与烟草有关的气体和颗粒,这些气体和颗粒嵌入到地毯、墙壁、家具、毯子和玩具等材料中。严格来说,THS不是烟雾,而是附着在表面上的化学物质,它们可以从表面释放回空气中,经历化学转化和/或积累。目前,THS的危害不如二手烟(SHS)的危害有据可查。在这个角度来看,我们描述的分布和发生的化学变化,SHS转化为THS,THS的环境污染的研究,人体暴露研究,毒理学研究,使用动物模型和体外系统,避免暴露的可能方法,THS污染的补救措施,以及进一步研究的优先事项。
Thirdhand smoke (THS) is the contamination that persists after secondhand tobacco smoke has been emitted into air. It refers to the tobacco-related gases and particles that become embedded in materials, such as the carpet, walls, furniture, blankets, and toys. THS is not strictly smoke, but chemicals that adhere to surfaces from which they can be released back into the air, undergo chemical transformations and/or accumulate. Currently, the hazards of THS are not as well documented as the hazards of secondhand smoke (SHS). In this Perspective, we describe the distribution and chemical changes that occur as SHS is transformed into THS, studies of environmental contamination by THS, human exposure studies, toxicology studies using animal models and in vitro systems, possible approaches for avoiding exposure, remediation of THS contamination, and priorities for further research.
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