Bone regeneration and stem cells.

Bone regeneration and stem cells.
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DOI:
10.1111/j.1582-4934.2010.01224.x
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发表时间:
2011-04
影响因子:
5.3
通讯作者:
Finne-Wistrand A
Finne-Wistrand A
中科院分区:
医学2区
文献类型:
--
作者:
Arvidson K;Abdallah BM;Applegate LA;Baldini N;Cenni E;Gomez-Barrena E;Granchi D;Kassem M;Konttinen YT;Mustafa K;Pioletti DP;Sillat T;Finne-Wistrand A

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本特邀综述涵盖了骨科和颌面骨组织修复的核心研究领域,包括正常骨折愈合和愈合问题,组织工程生物材料支架,间充质干细胞和胎儿干细胞,性类固醇对间充质干细胞的影响,富血小板血浆用于组织修复,成骨及其分子标记。讨论了除干细胞外的各种细胞,以及通过添加生物活性分子来满足骨和软组织再生特定要求的材料科学进展。
This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair, osteogenesis and its molecular markers. A variety of cells in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, are discussed.
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