Serum 25-hydroxyvitamin D levels among Boston trainee doctors in winter.

Serum 25-hydroxyvitamin D levels among Boston trainee doctors in winter.
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DOI:
10.3390/nu4030197
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发表时间:
2012-03
期刊:
影响因子:
5.9
通讯作者:
Mansbach JM
Mansbach JM
中科院分区:
医学2区
文献类型:
--
作者:
Growdon AS;Camargo CA Jr;Clark S;Hannon M;Mansbach JM

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作为室内工作者,实习医生可能面临维生素D不足的风险。波士顿儿科培训项目(住院医师)中的所有实习医生(住院医师)被邀请完成一项调查,并在2010年3月的3周内接受血清25-羟基维生素D [25(OH)D]、PTH和钙的检测。我们使用卡方检验、Kruskal-Wallis检验、多变量线性回归和逻辑回归分析了居民特征与血清25(OH)D之间的关系。在119名居民中,有102人(86%)参加。虽然平均血清25(OH)D水平为67 nmol/L(±26),但25例(25%)血清25(OH)D水平<50 nmol/L,3例(3%)居民血清25(OH)D水平<25 nmol/L。在多变量模型中,与25(OH)D水平相关的因素为:女性性(β 12.7,95% CI 3.6,21.7),白色人种(β 21.7,95% CI 11.7,31.7),在过去3个月内前往赤道纬度更高的地区(β 6.3,95% CI 2.0,10.5)和每日维生素D摄入量较高(β 1.1,95% CI 0.04,2.1)。尽管我们研究中四分之一的居民血清25(OH)D <50 nmol/L,但使用当前的医疗保险和医疗补助服务中心(CMS)筛查指南,所有人都将被遗漏。使用传统的危险因素似乎不足以确定低维生素D的室内工作者在北方纬度。
As indoor workers, trainee doctors may be at risk for inadequate vitamin D. All trainee doctors (residents) in a Boston pediatric training program (residency) were invited to complete a survey, and undergo testing for serum 25-hydroxyvitamin D [25(OH)D], PTH, and calcium during a 3-week period in March 2010. We examined the association between resident characteristics and serum 25(OH)D using Chi2 and Kruskal-Wallis test and multivariable linear and logistic regression. Of the 119 residents, 102 (86%) participated. Although the mean serum 25(OH)D level was 67 nmol/L (±26), 25 (25%) had a level <50 nmol/L and 3 (3%) residents had levels <25 nmol/L. In the multivariable model, factors associated with 25(OH)D levels were: female sex (β 12.7, 95% CI 3.6, 21.7), white race (β 21.7, 95% CI 11.7, 31.7), travel to more equatorial latitudes during the past 3 months (β 6.3, 95% CI 2.0, 10.5) and higher daily intake of vitamin D (β 1.1, 95% CI 0.04, 2.1). Although one in four residents in our study had a serum 25(OH)D <50 nmol/L, all of them would have been missed using current Centers for Medicare and Medicaid Services (CMS) screening guidelines. The use of traditional risk factors appears insufficient to identify low vitamin D in indoor workers at northern latitudes.
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