Influence of different geometric representations of the volume conductor on nerve activation during electrical stimulation.

Influence of different geometric representations of the volume conductor on nerve activation during electrical stimulation.
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DOI:
10.1155/2014/489240
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发表时间:
2014
影响因子:
--
通讯作者:
Yu W
Yu W
中科院分区:
工程技术4区
文献类型:
--
作者:
Gómez-Tames J;González J;Yu W

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具有不同几何表示的体积导体模型,诸如平行层模型(PM)、圆柱层模型(CM)或基于解剖学的模型(AM),已经在用于电刺激(FES)的生物电模型的实现期间被采用。评估它们的优势和局限性来预测神经激活是在准确性和计算时间之间实现良好平衡的基础。然而,没有旨在澄清以下问题的研究。(1)CM和PM之间的神经激活是否不同?(2)CM和PM在多大程度上近似于AM?(3)血管和神经干的存在对神经激活预测有什么影响?因此,在这项研究中,我们解决了这些问题,通过比较CM,PM和AM模型之间的神经激活FES。激活阈值用于评估在不同表面电极配置(尺寸和距离)、神经深度和刺激部位下的模型。此外,对人大腿的坐骨神经、股动脉和股静脉的影响进行了检查。结果表明,CM和PM有较高的误差率,但激活阈值的变化遵循与AM相同的电极尺寸和电极间距离的变化趋势。
Volume conductor models with different geometric representations, such as the parallel layer model (PM), the cylindrical layer model (CM), or the anatomically based model (AM), have been employed during the implementation of bioelectrical models for electrical stimulation (FES). Evaluating their strengths and limitations to predict nerve activation is fundamental to achieve a good trade-off between accuracy and computation time. However, there are no studies aimed at clarifying the following questions. (1) Does the nerve activation differ between CM and PM? (2) How well do CM and PM approximate an AM? (3) What is the effect of the presence of blood vessels and nerve trunk on nerve activation prediction? Therefore, in this study, we addressed these questions by comparing nerve activation between CM, PM, and AM models by FES. The activation threshold was used to evaluate the models under different configurations of superficial electrodes (size and distance), nerve depths, and stimulation sites. Additionally, the influences of the sciatic nerve, femoral artery, and femoral vein were inspected for a human thigh. The results showed that the CM and PM had a high error rate, but the variation of the activation threshold followed the same tendency for electrode size and interelectrode distance variation as AM.
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