The impact of COVID-19 pandemic on depression and anxiety symptoms: Findings from the United Arab Emirates Healthy Future (UAEHFS) cohort study.
The impact of COVID-19 pandemic on depression and anxiety symptoms: Findings from the United Arab Emirates Healthy Future (UAEHFS) cohort study.
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DOI：
10.1371/journal.pone.0277684
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
2019冠状病毒病大流行期间，人们对精神健康产生了重大担忧。我们调查了阿拉伯联合酋长国健康未来研究（UAEHFS）参与者中抑郁和焦虑症状的患病率;这是一项全国性队列研究。我们进一步探讨了具有可比的大流行前数据的人群中抑郁症状患病率的变化。UAEHFS参与者的样本被邀请在第一波疫情期间完成COVID-19在线问卷。采用患者健康问卷抑郁量表（PHQ-8）和广泛性焦虑量表（GAD-7）分别评定抑郁和焦虑症状。进行了非配对分析，以检查COVID-19对大流行期间抑郁和焦虑症状的影响。进行配对分析以检查抑郁症状的变化。在大流行期间，我们报告抑郁症的患病率为32.8%（95%CI：27.0，39.1），焦虑症状的患病率为26.4%（95%CI：21.0，32.6）。年轻人报告抑郁（40.4%）和焦虑（34.5%）症状水平较高。女性报告的抑郁（36.5%）和焦虑（32.7%）症状水平较高。在配对分析中，大流行期间抑郁症状的患病率为34%（95%CI：26.5，42.4），而大流行前为29.9%（95%CI：22.7，38.1）。未观察到统计学显著差异，p值= 0.440。在流感大流行期间，PHQ-8和GAD-7的校正多变量logistic回归模型显示，与没有症状的参与者相比，经历流感样症状的参与者报告抑郁症状的几率更高。此外，年龄与焦虑症状呈显著负相关。总体而言，我们发现抑郁和焦虑症状在年轻人和女性中更为普遍。然而，我们没有发现大流行前数据可比的人群中抑郁症状的患病率有显著变化。通过纵向研究确定弱势群体并了解其发展轨迹，将有助于规划针对当前和未来流行病的有效心理健康干预措施。
Significant concerns about mental health were raised during the COVID-19 pandemic. We investigated the prevalence of depression and anxiety symptoms among the participants of the United Arab Emirates Healthy Future Study (UAEHFS); a national cohort study. We further explored the change in the prevalence of depression symptoms among those with comparable pre-pandemic data. A sample of UAEHFS participants were invited to complete a COVID-19 online questionnaire during the first wave of the pandemic. Depression and anxiety symptoms were assessed using the Patient Health Questionnaire Depression Scale (PHQ-8) and the Generalized Anxiety Disorder-7 Scale (GAD-7) respectively. Unpaired analyses were done to examine the effect of COVID-19 on depression and anxiety symptoms during the pandemic. Paired analysis was conducted to examine the change in depression symptoms. During the pandemic, we reported a prevalence of 32.8% (95% CI: 27.0, 39.1) for depression and 26.4% (95% CI: 21.0, 32.6) for anxiety symptoms. Younger people reported higher levels of depression (40.4%) and anxiety (34.5%) symptoms. Females reported higher levels of depression (36.5%) and anxiety (32.7%) symptoms. In paired analysis, the prevalence of depression symptoms during the pandemic was 34% (95% CI: 26.5, 42.4) compared to 29.9% (95% CI: 22.7, 38.1) before the pandemic. No statistically significant difference was observed, p-value = 0.440. Adjusted multivariate logistic regression models for PHQ-8 and GAD-7 during the pandemic showed that participants, who were experiencing flu-like symptoms, had higher odds of reporting depression symptoms compared to those without symptoms. Additionally, age was significantly negatively associated with anxiety symptoms. Overall, we found that depression and anxiety symptoms were more prevalent among young people and females. However, we did not find a significant change in the prevalence of depression symptoms among those with comparable pre-pandemic data. Identifying vulnerable groups and understanding trajectories through longitudinal studies would help with planning for effective mental health interventions for the current and future pandemics.
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