Recollection, familiarity, and content-sensitivity in lateral parietal cortex: a high-resolution fMRI study.
Recollection, familiarity, and content-sensitivity in lateral parietal cortex: a high-resolution fMRI study.
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横向顶叶皮层中的回忆，熟悉度和内容敏感性：一项高分辨率fMRI研究。
DOI：
10.3389/fnhum.2013.00219
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发表时间：
2013
影响因子：
2.9
通讯作者：
Rugg MD
中科院分区：
文献类型：
--
作者：
Johnson JD;Suzuki M;Rugg MD
许多研究已经确定了大脑中活动与对定性情节信息的提取(回忆)一致相关的区域。根据检索内容的不同，这种“核心回忆网络”可以与活动不同的区域进行对比。本研究使用高分辨率功能磁共振成像来调查这些假定不同的提取过程是否涉及公共区域和可分离区域。受试者学习了两个编码任务的单词，然后进行了记忆测试，在测试中，他们区分了回忆和不同水平的识别置信度。研究和测试的fMRI数据揭示了几个重叠的区域，这些区域的活动根据编码任务的不同而不同，这表明内容在提取过程中被选择性地恢复。然而，大多数与回忆有关的区域没有表现出恢复效应，这为核心回忆网络提供了支持。重要的是，外侧顶叶皮质表现出明显的分离，回忆效应局限于角回，自信效应局限于顶内沟。此外，后一区域表现出非单调模式，与反映项目熟悉度的神经信号一致，而不是记忆强度的一般形式。综上所述，研究结果表明，情节提取依赖于内容敏感和核心回忆过程，这两个过程可以与基于熟悉度的再认记忆区分开来。
Numerous studies have identified brain regions where activity is consistently correlated with the retrieval (recollection) of qualitative episodic information. This ‘core recollection network’ can be contrasted with regions where activity differs according to the contents of retrieval. The present study used high-resolution fMRI to investigate whether these putatively-distinct retrieval processes engage common versus dissociable regions. Subjects studied words with two encoding tasks and then performed a memory test in which they distinguished between recollection and different levels of recognition confidence. The fMRI data from study and test revealed several overlapping regions where activity differed according to encoding task, suggesting that content was selectively reinstated during retrieval. The majority of recollection-related regions, though, did not exhibit reinstatement effects, providing support for a core recollection network. Importantly, lateral parietal cortex demonstrated a clear dissociation, whereby recollection effects were localized to angular gyrus and confidence effects were restricted to intraparietal sulcus. Moreover, the latter region exhibited a non-monotonic pattern, consistent with a neural signal reflecting item familiarity rather than a generic form of memory strength. Together, the findings show that episodic retrieval relies on both content-sensitive and core recollective processes, and these can be differentiated from familiarity-based recognition memory.
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影响因子：
2.4
作者：
Donaldson, W
通讯作者：
Donaldson, W
影响因子：
3
作者：
GREENHOUSE, SW;GEISSER, S
通讯作者：
GEISSER, S
影响因子：
25
作者：
Eldridge, LL;Knowlton, BT;Engel, SA
通讯作者：
Engel, SA
DOI：
10.1016/j.cub.2010.01.053
发表时间：
2010-03-23
期刊：
Current biology : CB
影响因子：
--
作者：
Chadwick MJ;Hassabis D;Weiskopf N;Maguire EA
通讯作者：
Maguire EA
影响因子：
5.3
作者：
Evans, Lisa H.;Wilding, Edward L.
通讯作者：
Wilding, Edward L.