Acceptability and performance of a directly assisted oral HIV self-testing intervention in adolescents in rural Mozambique.
Acceptability and performance of a directly assisted oral HIV self-testing intervention in adolescents in rural Mozambique.
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DOI：
10.1371/journal.pone.0195391
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Jefferys LF
中科院分区：
文献类型：
--
作者：
Hector J;Davies MA;Dekker-Boersema J;Aly MM;Abdalad CCA;Langa EBR;Ehmer J;Hobbins MA;Jefferys LF
尽管全球在艾滋病毒检测和治疗方面取得了进展，但在莫桑比克北方农村地区，艾滋病规划署的“90 90 90”目标仍然遥不可及。促进在难以接触到的群体中进行检测的新战略将有助于莫桑比克应对艾滋病毒流行病。艾滋病毒自我检测（HIVST）是世界卫生组织推荐的一种额外的方法，以增加对青少年的艾滋病毒检测服务。本研究评估了莫桑比克农村青少年直接辅助口服HIVST干预的可接受性和性能。16-20岁的青少年被纳入学校，并被邀请参加当地医院的青年友好服务，直接帮助口腔艾滋病毒/艾滋病治疗。获得基线和测试后问卷。使用OraQuick Rapid HIV-1/2 Antibody test®。结果由参与者和护士阅读。根据莫桑比克国家标准，通过手指点刺HIV试验（Determine® HIV 1/2 Alere和Unigold™ HIV Trinity Biotech）确认结果。在2016年9月至11月期间，496名青少年被纳入其中，其中299人进行了口服艾滋病毒自我检测。70%是第一次测试。阳性率为1.7%。青少年和护士之间的评价者之间的一致性为99.6%（Kappa 0.93），没有假阴性或假阳性结果的口服艾滋病毒自我检测。五次测试无效。7.1%的人认为测试很难使用。超过80%的人更喜欢直接辅助的HIVST，而不是标准的手指点刺试验。虽然20%的人认为在家里做艾滋病病毒检测是件好事，但76%的人更喜欢在健康中心做艾滋病病毒检测，原因包括增加安全性、隐私性和咨询师的存在。直接辅助口服HIVST是莫桑比克农村青少年的一种可行的干预措施，首次进行艾滋病毒检测者的结果令人鼓舞。
Whereas progress in HIV testing and treatment has been made globally, the UNAIDS goal of “90 90 90” is still out of sight in rural northern Mozambique. New strategies that promote testing in hard to reach groups will aid Mozambique’s response to the HIV epidemic. HIV self-testing (HIVST) is recommended by the WHO as an additional approach to augment the HIV testing services available to adolescents. This study evaluates acceptability and performance of a directly assisted oral HIVST intervention for adolescents in rural Mozambique. Adolescents aged 16–20 years were included at schools and invited to attend the local hospital’s youth friendly service for directly assisted oral HIVST. Baseline and post-test questionnaires were obtained. OraQuick Rapid HIV-1/2 Anti body test® was used. Results were read by the participant and by a nurse. Results were confirmed by finger prick HIV test (Determine® HIV 1/2 Alere and Unigold™ HIV Trinity Biotech) according to the Mozambican national standard. Between September and November 2016, 496 adolescents were included, of which 299 performed an oral HIV self-test. 70% were first time testers. The positivity rate was 1.7%. The inter-rater agreement between adolescent and nurse was 99.6% (kappa 0.93); there were no false negative or false positive results of the oral HIV self-test. Five tests were invalid. 7.1% found the test difficult to use. Over 80% preferred directly assisted HIVST compared to the standard finger prick testing. While 20% thought it would be good to do HIVST at home, 76% preferred to do HIVST at the health centre, for reasons including increased security, privacy, and the presence of a counsellor. Directly assisted oral HIVST is a feasible intervention for adolescents in rural Mozambique and showed encouraging results for first time HIV testers.
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影响因子：
4.5
作者：
Madiba S;Mokgatle M
通讯作者：
Mokgatle M
影响因子：
4.5
作者：
Marlin RW;Young SD;Bristow CC;Wilson G;Rodriguez J;Ortiz J;Mathew R;Klausner JD
通讯作者：
Klausner JD
影响因子：
1.6
作者：
Beksinska ME;Smit JA;Mantell JE
通讯作者：
Mantell JE
DOI：
10.1111/j.1552-6909.1996.tb02514.x
发表时间：
1996-01-01
期刊：
Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
影响因子：
--
作者：
Hiltabiddle, S J
通讯作者：
Hiltabiddle, S J
影响因子：
4.4
作者：
Kurth AE;Cleland CM;Chhun N;Sidle JE;Were E;Naanyu V;Emonyi W;Macharia SM;Sang E;Siika AM
通讯作者：
Siika AM