Osteoclast biology in the single-cell era.
Osteoclast biology in the single-cell era.
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DOI:
10.1186/s41232-022-00213-x
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发表时间:
2022-09-02
影响因子:
8.1
通讯作者:
中科院分区:
文献类型:
--
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Osteoclasts, the only cells that can resorb bone, play a central role in bone homeostasis as well as bone damage under pathological conditions such as osteoporosis, arthritis, periodontitis, and bone metastasis. Recent studies using single-cell technologies have uncovered the regulatory mechanisms underlying osteoclastogenesis at unprecedented resolution and shed light on the possibility that there is heterogeneity in the origin, function, and fate of osteoclast-lineage cells. Here, we discuss the current advances and emerging concepts in osteoclast biology.
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影响因子:
64.5
作者:
Baryawno, Ninib;Przybylski, Dariusz;Scadden, David T.
通讯作者:
Scadden, David T.
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10.5
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Dougall, WC;Glaccum, M;Schuh, J
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Schuh, J
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Cawley, Keisha M.;Bustamante-Gomez, Nancy Cecile;O'Brien, Charles A.
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O'Brien, Charles A.
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Galibert, L
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Blin-Wakkach, Claudine