A voxel-based morphometry (VBM) analysis of regional grey and white matter volume abnormalities within the speech production network of children who stutter.
A voxel-based morphometry (VBM) analysis of regional grey and white matter volume abnormalities within the speech production network of children who stutter.
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DOI：
10.1016/j.cortex.2012.08.013
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发表时间：
2013-09
期刊：
影响因子：
3.6
通讯作者：
De Nil, Luc F.
中科院分区：
文献类型：
--
作者：
Beal, Deryk S.;Gracco, Vincent L.;Brettschneider, Jane;Kroll, Robert M.;De Nil, Luc F.
关键词：
It is well documented that neuroanatomical differences exist between adults who stutter and their fluently speaking peers. Specifically, adults who stutter have been found to have more grey matter volume (GMV) in speech relevant regions including inferior frontal gyrus, insula and superior temporal gyrus. Despite stuttering having its onset in childhood only one study has investigated the neuroanatomical differences between children who do and do not stutter. reported children who stutter had less GMV in the bilateral inferior frontal gyri and middle temporal gyrus relative to fluently speaking children. Thus it appears that children who stutter present with unique neuroanatomical abnormalities as compared to those of adults who stutter. In order to better understand the neuroanatomical correlates of stuttering earlier in its development, near the time of onset, we used voxel-based morphometry to examine volumetric differences between 11 children who stutter and 11 fluent children. Children who stutter had less GMV in the bilateral inferior frontal gyri and left putamen but more GMV in right Rolandic operculum and superior temporal gyrus relative to fluent children. Children who stutter also had less white matter volume bilaterally in the forceps minor of the corpus callosum. We discuss our findings of widespread anatomic abnormalities throughout the cortical network for speech motor control within the context of the speech motor skill limitations identified in people who stutter.
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DOI：
10.1196/annals.1360.057
发表时间：
2005-01-01
期刊：
NEUROSCIENCES AND MUSIC II: FROM PERCEPTION TO PERFORMANCE
影响因子：
--
作者：
Bermudez, Patrick;Zatorre, Robert J.
通讯作者：
Zatorre, Robert J.
影响因子：
9.9
作者：
Foundas, AL;Bollich, AM;Heilman, KM
通讯作者：
Heilman, KM
影响因子：
9.9
作者：
Foundas, AL;Corey, DM;Heilman, KM
通讯作者：
Heilman, KM
影响因子：
11.2
作者：
Catani, M;Jones, DK;Ffytche, DH
通讯作者：
Ffytche, DH
影响因子：
2.1
作者：
Bauerly, Kim R.;De Nil, Luc F.
通讯作者：
De Nil, Luc F.