Implications of Oxidative Stress in the Pathogenesis and Treatment of Hyperpigmentation Disorders.
Implications of Oxidative Stress in the Pathogenesis and Treatment of Hyperpigmentation Disorders.
复制标题
氧化应激对色素沉着过度疾病发病机制和治疗的影响
DOI:
10.1155/2022/7881717
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发表时间:
2022
影响因子:
--
通讯作者:
Xiang L
中科院分区:
文献类型:
--
作者:
Xing X;Dan Y;Xu Z;Xiang L
Oxidative stress represents an imbalance between the generation of reactive oxygen and nitrogen species and the ability of antioxidant systems to decompose those products. Oxidative stress is implicated in the pathogenesis of hyperpigmentation, hypopigmentation, melanoma, and other skin diseases. Regulatory networks involving oxidative stress and related pathways are widely represented in hypopigmentation diseases, particularly vitiligo. However, there is no complete review into the role of oxidative stress in the pathogenesis of hyperpigmentation disorders, especially regarding associations involving oxidative stress and cellular signaling pathways. Here, we review oxidative and antioxidant systems, oxidative stress-induced signal transduction mechanisms, and effects of antioxidant drugs used in preclinical and clinical settings in hyperpigmentation disorders.
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影响因子:
2.9
作者:
Burke, KE;Clive, J;Nakamura, RM
通讯作者:
Nakamura, RM
影响因子:
--
作者:
Ayala A;Muñoz MF;Argüelles S
通讯作者:
Argüelles S
DOI:
10.3390/antiox10081315
发表时间:
2021-08-21
期刊:
Antioxidants (Basel, Switzerland)
影响因子:
--
作者:
Boo YC
通讯作者:
Boo YC
影响因子:
4
作者:
Choi, Wonseon;Wolber, Rainer;Hearing, Vincent J.
通讯作者:
Hearing, Vincent J.
DOI:
10.1067/s0190-9622(03)00900-9
发表时间:
2003-09-01
影响因子:
13.8
作者:
Burke, KE;Clive, J;Nakamura, RM
通讯作者:
Nakamura, RM