Functional connectivity and cognitive impairment in migraine with and without aura.

Functional connectivity and cognitive impairment in migraine with and without aura.
复制标题

DOI:
10.1186/s10194-017-0782-6
复制
发表时间:
2017-12
期刊:
The journal of headache and pain
影响因子:
--
通讯作者:
Marino S
Marino S
中科院分区:
其他
文献类型:
--
作者:
Lo Buono V;Bonanno L;Corallo F;Pisani LR;Lo Presti R;Grugno R;Di Lorenzo G;Bramanti P;Marino S

文献摘要

参考文献

被引文献

相似文献

几项针对偏头痛的功能磁共振成像研究评估了不同网络的静息态功能连接,表明这种神经系统疾病与大脑功能改变有关。本研究的目的是探讨在默认模式网络中,无先兆和有先兆偏头痛患者在发作间期发作期间认知功能与大脑功能连接之间的关联。连续招募了 28 名偏头痛患者(14 名无先兆,14 名有先兆)和 14 名匹配的正常对照。进行了一系列标准化神经心理学测试来评估认知功能,所有受试者都接受了静息状态下的高场功能磁共振成像检查。偏头痛患者在神经心理学评估中没有表现出异常,而如果我们比较有先兆和无先兆的偏头痛,我们发现皮质网络发生了特定的改变。我们观察到,在有先兆的偏头痛中,左侧角回、左侧边缘上回、右侧中央前回、右侧中央后回、右侧岛叶皮质的连通性增强。我们的研究结果表明,偏头痛患者的功能连接结构发生了改变。我们认为我们的结果可能有助于更好地了解偏头痛的发病机制。
Several fMRI studies in migraine assessed resting state functional connectivity in different networks suggesting that this neurological condition was associated with brain functional alteration. The aim of present study was to explore the association between cognitive functions and cerebral functional connectivity, in default mode network, in migraine patients without and with aura, during interictal episodic attack. Twenty-eight migraine patients (14 without and 14 with aura) and 14 matched normal controls, were consecutively recruited. A battery of standardized neuropsychological test was administered to evaluate cognitive functions and all subjects underwent a resting state with high field fMRI examination. Migraine patients did not show abnormalities in neuropsychological evaluation, while, we found a specific alteration in cortical network, if we compared migraine with and without aura. We observed, in migraine with aura, an increased connectivity in left angular gyrus, left supramarginal gyrus, right precentral gyrus, right postcentral gyrus, right insular cortex. Our findings showed in migraine patients an alteration in functional connectivity architecture. We think that our results could be useful to better understand migraine pathogenesis.
偏头痛患者静息状态下的大脑活动:脑磁图研究
DOI: 10.1186/s10194-015-0525-5
发表时间: 2015-01-01
期刊: The journal of headache and pain
影响因子: --
作者:
Liu, Hongxing;Ge, Huaiting;Wang, Xiaoshan
通讯作者: Wang, Xiaoshan
DOI: 10.1523/jneurosci.5173-08.2009
发表时间: 2009-03-04
期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子: --
作者:
Starr CJ;Sawaki L;Wittenberg GF;Burdette JH;Oshiro Y;Quevedo AS;Coghill RC
通讯作者: Coghill RC
DOI: 10.1186/s10194-016-0667-0
发表时间: 2016-12
期刊: The journal of headache and pain
影响因子: --
作者:
Santangelo G;Russo A;Trojano L;Falco F;Marcuccio L;Siciliano M;Conte F;Garramone F;Tessitore A;Tedeschi G
通讯作者: Tedeschi G
DOI: 10.1002/hbm.10062
发表时间: 2002-11-01
影响因子: 4.8
作者:
Smith, SM
通讯作者: Smith, SM
DOI: 10.1006/nimg.2002.1132
发表时间: 2002-10-01
期刊: NEUROIMAGE
影响因子: 5.7
作者:
Jenkinson, M;Bannister, P;Smith, S
通讯作者: Smith, S