Reversed laminar appearance of articular cartilage by T1-weighting in 3D fat-suppressed spoiled gradient recalled echo (SPGR) imaging.
Reversed laminar appearance of articular cartilage by T1-weighting in 3D fat-suppressed spoiled gradient recalled echo (SPGR) imaging.
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DOI：
10.1002/jmri.22278
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发表时间：
2010-09
影响因子：
4.4
通讯作者：
Zheng, Shaokuan
中科院分区：
文献类型：
--
作者：
Xia, Yang;Zheng, Shaokuan
目的探讨三维脂肪抑制梯度回忆回波（FS-SPGR）成像在关节软骨层状外观中的反向强度模式。三维SPGR实验在犬关节软骨上进行，回声时间（TE）为2.12 ms，重复时间（TR）为60ms，不同翻转角度（5°~ 80°）。此外，对软骨进行T1、T2和T2*成像，用于解释SPGR成像中层状的出现。软骨中T2和T2*的形态相似。在26 μm像元分辨率下，多重梯度回波成像序列的T2值约为单次自旋回波成像序列的1/3。自旋回波成像软骨层状表现主要由t2加权引起，而幻角快速成像（即短TR）软骨层状表现可呈现相反的强度格局，主要由t1加权引起。关节软骨的层状外观在组织深部可能具有相反的强度模式，这取决于图像是t1加权还是t2加权。在MRI检查软骨图像时，应同时考虑潜在的分子结构和实验方案。
To investigate the reversed intensity pattern in the laminar appearance of articular cartilage by 3D Fat-Suppressed Spoiled Gradient Recalled Echo (FS-SPGR) imaging in MRI. The 3D SPGR experiments were carried out on canine articular cartilage with an echo time (TE) of 2.12 ms, a repetition time (TR) of 60ms, and various flip-angles (5°–80°). In addition, T1, T2 and T2* in cartilage were imaged and used to explain the laminar appearance in SPGR imaging. The profiles of T2 and T2* in cartilage were similar in shape. However, the T2 values from the multi-gradient-echo imaging sequence were about 1/3 of those from single spin-echo sequences at a pixel resolution of 26 μm. While the laminar appearance of cartilage in spin-echo imaging is caused mostly by T2-weighting, the laminar appearance of cartilage in fast imaging (i.e., short TR) at the magic angle can have a reversed intensity pattern, which is caused mostly by T1-weighting. Laminar appearance of articular cartilage can have the opposite intensity patterns in the deep part of the tissue, depending upon whether the image is T1-weighted or T2-weighted. The underlying molecular structure and experimental protocols should both be considered when one examines cartilage images in MRI.
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影响因子：
19.7
作者：
RECHT, MP;KRAMER, J;RESNICK, D
通讯作者：
RESNICK, D
影响因子：
2.2
作者：
Zheng, ShaoKuan;Xia, Yang
通讯作者：
Xia, Yang
影响因子：
5
作者：
DISLER, DG;PETERS, TL;RIFKIN, MD
通讯作者：
RIFKIN, MD
影响因子：
3.3
作者：
MAJUMDAR, S;GORE, JC
通讯作者：
GORE, JC
影响因子：
3.3
作者：
XIA, Y;FARQUHAR, T;JELINSKI, LW
通讯作者：
JELINSKI, LW