The immune epitope database (IEDB) 3.0.

The immune epitope database (IEDB) 3.0.
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DOI:
10.1093/nar/gku938
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发表时间:
2015-01
影响因子:
14.9
通讯作者:
Peters B
Peters B
中科院分区:
生物学2区
文献类型:
--
作者:
Vita R;Overton JA;Greenbaum JA;Ponomarenko J;Clark JD;Cantrell JR;Wheeler DK;Gabbard JL;Hix D;Sette A;Peters B

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IEDB,www.iedb.org,包含免疫表位的信息-适应性免疫反应的分子靶点-从已发表的文献中精选,并由国立卫生研究院资助的表位发现工作提交。从2004年到2012年,IEDB对自1960年以来发表的期刊文章的管理已经赶上了今天,超过95%的相关出版文献手动管理,迄今为止超过15,000篇期刊文章和704,000多个实验。自2012年以来,修订后的策展目标是在IEDB中快速提供最新的研究结果,从而确保它继续成为最新的资源。在IEDB中收集了全面的数据集后,在IEDB 3.0版本中对查询和报告界面进行了全面的重新设计,以改善最终用户如何以直观和生物准确的方式访问这些信息。我们在这里介绍IEDB的最新版本,并描述用户测试程序以及启用它的外部本体的使用。
The IEDB, www.iedb.org, contains information on immune epitopes—the molecular targets of adaptive immune responses—curated from the published literature and submitted by National Institutes of Health funded epitope discovery efforts. From 2004 to 2012 the IEDB curation of journal articles published since 1960 has caught up to the present day, with >95% of relevant published literature manually curated amounting to more than 15 000 journal articles and more than 704 000 experiments to date. The revised curation target since 2012 has been to make recent research findings quickly available in the IEDB and thereby ensure that it continues to be an up-to-date resource. Having gathered a comprehensive dataset in the IEDB, a complete redesign of the query and reporting interface has been performed in the IEDB 3.0 release to improve how end users can access this information in an intuitive and biologically accurate manner. We here present this most recent release of the IEDB and describe the user testing procedures as well as the use of external ontologies that have enabled it.
DOI: 10.1093/nar/gks1146
发表时间: 2013-01
影响因子: 14.9
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期刊: PLOS ONE
影响因子: 3.7
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通讯作者: Sette, Alessandro