Sleep and sadness: exploring the relation among sleep, cognitive control, and depressive symptoms in young adults.
Sleep and sadness: exploring the relation among sleep, cognitive control, and depressive symptoms in young adults.
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DOI：
10.1016/j.sleep.2013.10.006
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发表时间：
2014-01
期刊：
影响因子：
4.8
通讯作者：
Schnyer, David M.
中科院分区：
文献类型：
--
作者：
Vanderlind, W. Michael;Beevers, Christopher G.;Sherman, Stephanie M.;Trujillo, Logan T.;McGeary, John E.;Matthews, Michael D.;Maddox, W. Todd;Schnyer, David M.
睡眠障碍是抑郁症的一个常见特征。然而，最近的研究发现，与低风险人群相比，易患抑郁症的人的睡眠质量较差，这表明睡眠障碍可能先于抑郁症发生。此外，睡眠障碍和抑郁症都与认知控制过程的缺陷有关。因此，我们研究了睡眠质量差是否预示着抑郁症状的随后增加，以及认知控制水平是否介导了这种关系。 35 名本科生参加了 2 期实验，实验期相隔 3 周。参与者在两次会议之间佩戴活动记录仪手表，这可以客观地测量睡眠模式。我们在两次治疗期间评估了自我报告的睡眠质量和抑郁症状。最后，参与者完成了一项外源提示任务，该任务测量在第二次会议期间将注意力从中性和负面刺激中分离出来的能力。通过路径分析，我们发现，更大的自我报告睡眠困难和更客观的睡眠稳定性测量都显着预示着将注意力从负面刺激中分离出来的难度更大（即认知控制更少）。对负面刺激的认知控制较少反过来预示着第二次治疗时抑郁症状会增加。还提出了昼夜运动输出周期 kaput 基因、CLOCK、单核苷酸多态性 (SNP)、rs11932595 以及睡眠评估和抑郁症状之间的探索性关联。这些初步结果表明，睡眠中断可能通过影响认知控制而导致抑郁症状的增加。此外，CLOCK基因的变异可能与睡眠质量有关。
Sleep disturbance is a common feature of depression. However, recent work has found that individuals who are vulnerable to depression report poorer sleep quality compared to their low-risk counterparts, suggesting that sleep disturbance may precede depression. In addition, both sleep disturbance and depression are related to deficits in cognitive control processes. Thus we examined if poor sleep quality predicts subsequent increases in depressive symptoms and if levels of cognitive control mediated this relation. Thirty-five undergraduate students participated in 2 experimental sessions separated by 3 weeks. Participants wore an actigraph watch between sessions, which provided an objective measure of sleep patterns. We assessed self-reported sleep quality and depressive symptoms at both sessions. Last, individuals completed an exogenous cuing task, which measured ability to disengage attention from neutral and negative stimuli during the second session. Using path analyses, we found that both greater self-reported sleep difficulty and more objective sleep stability measures significantly predicted greater difficulty disengaging attention (i.e., less cognitive control) from negative stimuli. Less cognitive control over negative stimuli in turn predicted increased depression symptoms at the second session. Exploratory associations among the circadian locomotor output cycles kaput gene, CLOCK, single nucleotide polymorphism (SNP), rs11932595, as well as sleep assessments and depressive symptoms also are presented. These preliminary results suggest that sleep disruptions may contribute to increases in depressive symptoms via their impact on cognitive control. Further, variation in the CLOCK gene may be associated with sleep quality.
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DOI：
10.1097/00002060-200105000-00003
发表时间：
2001-05-01
影响因子：
3
作者：
Fichtenberg, NL;Putnam, SH;Millard, AE
通讯作者：
Millard, AE
影响因子：
1.8
作者：
Berle, Jan O;Hauge, Erik R;Fasmer, Ole B
通讯作者：
Fasmer, Ole B
影响因子：
2
作者：
SOKOLOVE, PG;BUSHELL, WN
通讯作者：
BUSHELL, WN
DOI：
10.1093/geronb/gbn037
发表时间：
2009-03-01
影响因子：
6.2
作者：
Nebes, Robert D.;Buysse, Daniel J.;Monk, Timothy H.
通讯作者：
Monk, Timothy H.
影响因子：
5.6
作者：
BONNET, MH
通讯作者：
BONNET, MH