MicroRNA mediated regulation of immunity against gram-negative bacteria.
MicroRNA mediated regulation of immunity against gram-negative bacteria.
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DOI：
10.1080/08830185.2017.1347649
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发表时间：
2017-09-03
影响因子：
5
通讯作者：
Arulanandam BP
中科院分区：
文献类型：
--
作者：
Keck J;Gupta R;Christenson LK;Arulanandam BP
Evidence over the last couple decades has comprehensively established that short, highly conserved, non-coding RNA species called microRNA (miRNA) exhibit the ability to regulate expression and function of host genes at the messenger RNA (mRNA) level. MicroRNAs play key regulatory roles in immune cell development, differentiation, and protective function. Intrinsic host immune response to invading pathogens rely on intricate orchestrated events in the development of innate and adaptive arms of immunity. We discuss the involvement of miRNAs in regulating these processes against gram negative pathogens in this review.
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