Exosomes as novel biomarkers in metabolic disease and obesity-related cancers.
Exosomes as novel biomarkers in metabolic disease and obesity-related cancers.
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DOI:
10.1038/s41574-022-00666-7
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发表时间:
2022-06
影响因子:
40.5
通讯作者:
Denis, Gerald V.
中科院分区:
文献类型:
--
作者:
Jafari, Naser;Llevenes, Pablo;Denis, Gerald V.
Exosomes include plasma-transported vesicles that are secreted by human tissues and reflect metabolic status. The profile of exosomes (particularly microRNA content) is altered in metabolic disease. In type 2 diabetes mellitus, exosomes circulating in plasma induce transcriptional changes related to tumour progression and pro-metastatic phenotypes in target cancer cells, potentially linking obesity to cancer progression and metastasis.
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影响因子:
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作者:
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通讯作者:
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影响因子:
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DOI:
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发表时间:
2022
期刊:
Diabetes, metabolic syndrome and obesity : targets and therapy
影响因子:
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作者:
Yang X;Wu N
通讯作者:
Wu N
影响因子:
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作者:
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