Cardiovascular health and arterial stiffness: the Maine-Syracuse Longitudinal Study.
Cardiovascular health and arterial stiffness: the Maine-Syracuse Longitudinal Study.
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DOI：
10.1038/jhh.2013.131
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发表时间：
2014-07
影响因子：
2.7
通讯作者：
中科院分区：
文献类型：
--
作者：
理想的心血管健康是美国心脏协会（AHA）最近定义的一个概念，旨在促进心血管疾病的减少。动脉硬化是心血管疾病的主要危险因素。多种流行心血管危险因素和健康行为的存在与动脉僵硬度的相关程度尚不清楚。本研究的目的是检查AHA心血管健康和动脉僵硬度之间的关系，以脉搏波速度和脉压为指标。AHA健康指标，包括四个健康行为（吸烟，体重指数，身体活动和饮食）和三个健康因素（总胆固醇，血压和空腹血糖）在缅因州雪城纵向研究的505名参与者中进行了评估。结果指标为4 - 5年随访时测量的颈动脉-股动脉脉搏波速度（PWV）和脉压。更好的心血管健康，包括健康因素和行为，与较低的动脉硬度相关，如脉搏波速度和脉压所示。那些至少有5个健康指标处于理想水平的人的PWV（9.8 m/s）显著低于那些有2个或更少理想健康指标的人（11.7 m/s）（P<0.001）。增加人口统计学和PWV相关变量后，这一结果仍然存在（P=0.004）。
Ideal cardiovascular health is a recently defined construct by the American Heart Association (AHA) to promote cardiovascular disease reduction. Arterial stiffness is a major risk factor for cardiovascular disease. The extent to which the presence of multiple prevalent cardiovascular risk factors and health behaviors is associated with arterial stiffness is unknown. The aim of this study was to examine the association between the AHA construct of cardiovascular health and arterial stiffness, as indexed by pulse wave velocity and pulse pressure. The AHA health metrics, comprising of four health behaviors (smoking, body mass index, physical activity, and diet) and three health factors (total cholesterol, blood pressure, and fasting plasma glucose) were evaluated among 505 participants in the Maine-Syracuse Longitudinal Study. Outcome measures were carotid-femoral pulse wave velocity (PWV) and pulse pressure measured at 4 to 5-year follow-up. Better cardiovascular health, comprising both health factors and behaviors, was associated with lower arterial stiffness, as indexed by pulse wave velocity and pulse pressure. Those with at least five health metrics at ideal levels had significantly lower PWV (9.8 m/s) than those with two or less ideal health metrics (11.7 m/s) (P<0.001). This finding remained with the addition of demographic and PWV-related variables (P=0.004).
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DOI：
10.1161/hypertensionaha.109.147850
发表时间：
2010-04
期刊：
Hypertension (Dallas, Tex. : 1979)
影响因子：
--
作者：
Dengo AL;Dennis EA;Orr JS;Marinik EL;Ehrlich E;Davy BM;Davy KP
通讯作者：
Davy KP
影响因子：
3.3
作者：
Elias, Merrill F.;Robbins, Michael A.;Bates, Christopher J.
通讯作者：
Bates, Christopher J.
影响因子：
8.3
作者：
McEniery, Carmel M.;Spratt, Michael;Wilkinson, Ian B.
通讯作者：
Wilkinson, Ian B.
影响因子：
4.9
作者：
van Popele, Nicole M.;Mattace-Raso, Francesco U. S.;Witteman, Jacqueline C. M.
通讯作者：
Witteman, Jacqueline C. M.
影响因子：
8.3
作者：
Crichton, Georgina E.;Elias, Merrrill F.;Robbins, Michael A.
通讯作者：
Robbins, Michael A.