Enrichment and purification of pedunculoside and syringin from the barks of Ilex rotunda with macroporous resins.
Enrichment and purification of pedunculoside and syringin from the barks of Ilex rotunda with macroporous resins.
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DOI：
10.1080/10826076.2012.749499
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发表时间：
2014-02-01
影响因子：
1.3
通讯作者：
Ito Y
中科院分区：
文献类型：
--
作者：
Wang C;Chao Z;Sun W;Wu X;Ito Y
Jiubiying, the dried barks of Ilex rotunda Thunb. (Aquifoliaceae), has been used as herbal tea and traditional Chinese medicine for heat-clearing, detoxifying, dehumidification, and odynolysis. Pedunculoside and syringin are two main bioactive components. For the new drug development, we tried to isolate and purify several chemical constituents from Jiubiying by high-speed counter-current chromatography (HSCCC). The two-phase solvent system used was composed of ethyl acetate-n-butanol-water (1:6:7, v/v/v). From 1.0 g of Jiubiying extracts syringaresinol 4′,4″-bis-O-β-D- glucopyranoside (I, 20.2 mg), syringin (II, 56.8 mg), sinapaldehyde glucoside (III, 26.2 mg), syringaresinol 4′-O-β-D-glucopyranoside (IV, 20.4 mg), and pedunculoside (V, 45.1 mg) were obtained by one run of TBE-1000A HSCCC machine with 1000 mL of column volume. Their structures were identified by IR, MS, and extensive NMR studies. Syringaresinol 4′,4″-bis-O-β-D-glucopyranoside (I) was isolated from this plant for the first time.
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影响因子：
4.1
作者：
Fu, Yujie;Zu, Yuangang;Tong, Meihong
通讯作者：
Tong, Meihong
影响因子：
3.8
作者：
Jahromi, MAF;Gupta, M;Chansouria, JPN
通讯作者：
Chansouria, JPN
影响因子：
15
作者：
Langmuir, I
通讯作者：
Langmuir, I
影响因子：
4.1
作者：
Jia, Guangtao;Lu, Xiuyang
通讯作者：
Lu, Xiuyang
影响因子：
15
作者：
Langmuir, Irving
通讯作者：
Langmuir, Irving